Immediate Lymphatic Repair at Lymph Node Surgery for Melanoma Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional pilot study looks at performing lymphovenous bypass at the time of axillary or inguinal lymph node dissection in melanoma patients. It will measure how often lymphedema occurs within the first year after surgery, plus wound complications in 30 days, drain removal timing, and patient-reported quality of life. The study tracks LE prevalence at 3, 6, and 12 months, and estimates the time to first LE and cumulative incidence. LYMQOL is used to assess survivorship and lifestyle impact during follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Participants greater than or equal to 18 years of age.
2. Participants willing to participate.
3. Participants able to complete informed consent.
4. Participants with a diagnosis of Melanoma undergoing ALND or ILND.

Exclusion Criteria:

1. Participant staking anticoagulants within 7 days prior to surgery.
2. Participants that are known to be pregnant at the time of surgery.
3. Participants with BMI greater than 50.0

Where it's running

• MD Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Ashleigh M Francis, MD — M.D. Anderson Cancer Center
• Study coordinator: Ashleigh M Francis, MD
• Email: amfrancis@mdanderson.org
• Phone: (713) 413-7451

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Assessing outcomes of immediate lymphatic reconstruction to prevent lymphedema

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  Recruiting University of Chicago · Chicago, Illinois · NCT06650592

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• Observing surgical techniques for right-sided colon cancer treatment

  This study is testing different surgical methods for treating right-sided colon cancer to see if more extensive surgery can improve outcomes compared to standard techniques.

  Recruiting Haukeland University Hospital · Bergen · NCT06329102

• Lymphovenous bypass procedure to prevent lymphedema after lymphadenectomy

  This study is testing if a special surgery called lymphovenous bypass can help prevent swelling in the legs after patients have lymph nodes removed.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT05992909

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.