Assessing outcomes of immediate lymphatic reconstruction to prevent lymphedema
Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
This study is testing if a new surgery called immediate lymphatic reconstruction can help prevent lymphedema in people who have had lymph nodes removed.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 90 (estimated) |
| Sex | All |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT06650592 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effectiveness of immediate lymphatic reconstruction (ILR), a surgical technique performed during lymph node dissection to prevent lymphedema. The procedure involves connecting lymphatic channels to a local vein to facilitate lymphatic drainage in the upper extremities. Conducted at the University of Chicago Comprehensive Cancer Center, this study aims to gather high-level evidence on the efficacy of ILR, which is currently not widely covered by insurance and only available at select centers. The research will leverage the center's expertise in microsurgery and its designation as a Lymphedema Center of Excellence.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who are eligible for immediate lymphatic reconstruction following lymph node dissection.
Not a fit: Patients who are not candidates for immediate lymphatic reconstruction will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of lymphedema in patients undergoing lymph node dissection.
How similar studies have performed: While immediate lymphatic reconstruction is a novel approach, similar studies have shown promise in preventing lymphedema, although high-level evidence is still lacking.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who were candidates for Immediate Lymphatic Reconstruction (ILR) Exclusion Criteria: * None
Where this trial is running
Chicago, Illinois
- The University o Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Summer Hanson, MD, PhD, FACS — University of Chicago
- Study coordinator: Summer Hanson, MD, PhD, FACS
- Email: sehanson@bsd.uchicago.edu
- Phone: (773) 702-6302
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.