Assessing outcomes of immediate lymphatic reconstruction to prevent lymphedema
Official title: Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
Run by University of Chicago · NCT06650592 · Data updated 2026-11-12
This study is testing if a new surgery called immediate lymphatic reconstruction can help prevent lymphedema in people who have had lymph nodes removed.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | November 26, 2024 |
| Main results expected | October 2029 |
| Study ends | October 2029 |
| Registry record updated | February 2, 2026 |
| Trial ID | NCT06650592 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients who are eligible for immediate lymphatic reconstruction following lymph node dissection.
✕Probably not a fit
Patients who are not candidates for immediate lymphatic reconstruction will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates the effectiveness of immediate lymphatic reconstruction (ILR), a surgical technique performed during lymph node dissection to prevent lymphedema. The procedure involves connecting lymphatic channels to a local vein to facilitate lymphatic drainage in the upper extremities. Conducted at the University of Chicago Comprehensive Cancer Center, this study aims to gather high-level evidence on the efficacy of ILR, which is currently not widely covered by insurance and only available at select centers. The research will leverage the center's expertise in microsurgery and its designation as a Lymphedema Center of Excellence.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of lymphedema in patients undergoing lymph node dissection.
How similar studies have gone: While immediate lymphatic reconstruction is a novel approach, similar studies have shown promise in preventing lymphedema, although high-level evidence is still lacking.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who were candidates for Immediate Lymphatic Reconstruction (ILR) Exclusion Criteria: * None
Where it's running
-
The University o Chicago
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Summer Hanson, MD, PhD, FACS — University of Chicago
- Study coordinator: Summer Hanson, MD, PhD, FACS
- Email: sehanson@bsd.uchicago.edu
- Phone: (773) 702-6302
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Outcomes after immediate lymphatic reconstruction
This protocol will follow people having immediate lymphatic reconstruction during lymph node surgery to see if the procedure prevents lymphedema.
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Immediate Lymphatic Repair at Lymph Node Surgery for Melanoma Patients
This study tests whether doing a lymphovenous bypass during lymph node removal for melanoma can help prevent lymphedema and improve recovery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.