Assessing lymph node removal quality during minimally invasive gastric cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the effectiveness of a new scoring system, the PhotoNodes Score, to assess the quality of D2 lymphadenectomy during minimally invasive surgeries for gastric adenocarcinoma. The study aims to determine if this score can reliably indicate the absence of residual lymph nodes, which may correlate better with patient survival outcomes than the total number of nodes removed. It involves multiple centers and includes patients undergoing either upfront surgery or those treated with neoadjuvant chemotherapy. The goal is to improve surgical assessment and potentially enhance patient outcomes in gastric cancer treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients undergoing minimally invasive curative-intent surgery for gastric adenocarcinoma with D2 lymphadenectomy
* Patients undergoing upfront surgery or treated with a neoadjuvant/perioperative chemotherapy
* Total or Subtotal Gastrectomy
* Laparoscopic or Robotic approach

Exclusion Criteria:

* Age less than 18 year old
* Esophago-gastric junction cancer Siewert type I, II or III
* Metastatic disease
* Lymphadenectomy less than D2
* Open surgery
* Conversion to open surgery
* Palliative gastrectomy
* R1 or R2 resection
* Multivisceral resection except for cholecystectomy
* Surgical procedures other than subtotal or total gastrectomy
* A single node station rated as unevaluable by more than one reviewer

Where it's running

• Ospedale di Cremona - UOC Chirurgia Generale
  Cremona, Cr, Italy Recruiting
• Azienda Ospedaliera Universitaria Careggi - Chirurgia dell'Apparato Digerente
  Florence, Fi, Italy Recruiting
• Istituto Europeo di Oncologia
  Milan, Mi, Italy Recruiting
• ASST Grande Ospedale Metropolitano Niguarda
  Milan, Mi, Italy Recruiting
• Policlinico Abano
  Abano Terme, Pd, Italy Recruiting
• Azienda Ospedaliera Universitaria Integrata Borgo Trento - Chirurgia Generale ed Esofago Stomaco
  Verona, Vr, Italy Recruiting

Study contacts

• Principal investigator: Federico Marchesi, Prof. — Azienda Ospedaliero-Universitaria di Parma
• Study coordinator: Federico Marchesi, Prof
• Email: federico.marchesi@unipr.it
• Phone: 00390521906343

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.