Evaluating e-cigarettes versus traditional quit methods for smoking cessation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses whether non-cigarette tobacco products, specifically e-cigarettes, can aid smokers in quitting compared to traditional methods like nicotine replacement therapy or varenicline (Chantix). Participants will be randomly assigned to either an e-cigarette group, where they can choose brands and flavors, or a medication group, where they can select between nicotine patches, lozenges, or varenicline. The study will last for six months, involving weekly phone calls for the first seven weeks, followed by an 11-week call and a six-month follow-up visit. Participants will also maintain electronic daily diaries during the initial seven weeks to track their progress and experiences.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Adults 21+ who previously had a quit attempt using FDA-approved pharmacotherapy.
* Interest in reducing harms from tobacco use or quitting smoking

Exclusion Criteria

* Pregnant, breastfeeding, or trying to become pregnant.
* Household member currently enrolled in the study
* Planning to move out of the area within the next 7 months

Where it's running

• Medical Univeristy of South Carolina
  Charleston, South Carolina, United States Recruiting

Study contacts

• Principal investigator: Tracy Smith — smithtra@musc.edu
• Study coordinator: Tracy Smith, PhD
• Email: smithtra@musc.edu
• Phone: (843)-792-5164

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Stopping smoking before bronchoscopy or CT‑guided lung biopsy

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  Recruiting RWTH Aachen University · Aachen, North Rhine-Westphalia · NCT07322796

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.