Stopping smoking before bronchoscopy or CT‑guided lung biopsy
Smoking Cessation Before Intervention in Patients With Pulmonary Nodules Requiring Further Diagnosis
RWTH Aachen University · NCT07322796
This project tests whether offering immediate quit-smoking support and measuring nicotine markers helps people who smoke and are having a bronchoscopy or CT‑guided lung biopsy stop smoking.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 25 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | RWTH Aachen University (other) |
| Drugs / interventions | radiation |
| Locations | 1 site (Aachen, North Rhine-Westphalia) |
| Trial ID | NCT07322796 on ClinicalTrials.gov |
What this trial studies
This is an observational program for people who currently smoke and present with a suspicious round lung lesion; they are urgently advised to quit and offered connections to smoking‑cessation counseling and pharmacotherapy if desired. Nicotine dependence is measured with the Fagerström test and biochemical markers (COHb from blood gas and urine cotinine) are taken at baseline, at the planned result discussion after inpatient histological confirmation (bronchoscopy or CT‑guided puncture), and again at 3 months. The team also records age, gender, height, weight, medications, comorbidities, and body plethysmography data. Participation does not change the clinical course or treatment decisions for the diagnostic workup.
Who should consider this trial
Good fit: Active smokers who present to the pneumology outpatient clinic for evaluation of a suspicious pulmonary nodule and who are willing to participate in counseling and biochemical testing are ideal candidates.
Not a fit: People who do not smoke, who are unwilling to engage in cessation efforts, or who have medical conditions or treatments that make study measurements unevaluable are unlikely to benefit from this program.
Why it matters
Potential benefit: If successful, more patients with suspicious lung nodules may quit smoking, lowering their future risk of tobacco‑related illness and improving overall health outcomes.
How similar studies have performed: Smoking-cessation counseling with biochemical verification has helped smokers quit in other clinical settings, although applying it specifically around bronchoscopy or CT‑guided biopsy timing is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The patient is an active smoker by the time of the initial presentation in our pneumological outpatient clinic for the clarification of a suspicious nodule Exclusion Criteria: * Current or past medically relevant illness or treatment that could affect the evaluability of the study. * Expected lack of willingness to actively participate in study-related measures.
Where this trial is running
Aachen, North Rhine-Westphalia
- University RWTH Aachen — Aachen, North Rhine-Westphalia, Germany (RECRUITING)
Study contacts
- Study coordinator: Maria Aetou Dr.med
- Email: maetou@ukaachen.de
- Phone: 00492418088763
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Nodule, Solitary, Smoking Behaviors, smoking, smoking cessation, pulmonary nodules