Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Drone-delivered AEDs for cardiac arrests in rural areas

Official title: Developing and Testing Drone-Delivered AEDs for Cardiac Arrests In Rural America

Run by Duke University · NCT06229418 · Data updated 2026-11-12

This project tests whether delivering AEDs by emergency drones to out-of-hospital cardiac arrest sites can reach patients faster than current first responders and EMS in rural communities.

More Cardiac Arrest trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment4 (estimated)
SponsorDuke University
Academic / other
Locations1 site (Clemmons, North Carolina)
StatusRecruiting
StartedSeptember 8, 2025
Main results expectedMarch 31, 2027
Study endsJune 30, 2027
Registry record updatedOctober 1, 2026
Trial IDNCT06229418 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with non-traumatic cardiac arrest recorded in the CARES registry treated by or before 911 arrival.

Probably not a fit

Patients whose cardiac arrest is traumatic or not captured in CARES data may not benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project designs and pilots a drone-based AED delivery system for rural areas and assesses how quickly it can reach OHCA locations compared with traditional response times. It includes determining drone station configurations and optimizing AED placement, plus integrating drone delivery with existing FAA-approved programs. The pilot tests the safety and practicality in 2 urban and 4 rural communities, focusing on rapid AED access during cardiac arrests. The study uses CARES registry data to understand current outcomes and to inform program design. Aim 3 pilots are conducted in Forsyth County, NC and James City County, VA to evaluate real-world viability.

Why it matters

Potential benefit: If successful, drone-delivered AEDs could shorten the time to first defibrillation and potentially improve survival from OHCA in rural areas.

How similar studies have gone: Prior drone-delivery initiatives have shown feasibility; this trial advances proof-of-concept in rural settings with real-world pilots.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients 18 years of age or older in the CARES registry who suffer cardiac arrest before arrival of a 911-responder of non-traumatic cause, including patients who receive an AED shock by a bystander prior to the arrival of 911 responders.

Exclusion Criteria:

* Patients in the CARES registry who have a traumatic cause of cardiac arrest.

Where it's running

  • Forsyth County
    Clemmons, North Carolina, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.