Diode Laser vs LED for Faster Upper Canine Movement in Braces
Official title: Comparative Effects of Diode Laser and LED Photobiomodulation on Maxillary Canine Retraction During Orthodontic Treatment
Run by Can Tho University of Medicine and Pharmacy · NCT07810699 · Data updated 2026-11-12
In people needing braces, this study tests whether diode laser photobiomodulation moves the upper canine faster than LED photobiomodulation when both sides are treated in the same person.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 40 Years |
| Sex | All |
| Enrollment | 34 (estimated) |
| Sponsor | Can Tho University of Medicine and Pharmacy Academic / other |
| Locations | 1 site (Can Tho) |
| Status | Recruiting |
| Started | January 3, 2026 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT07810699 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with Class I malocclusion requiring bilateral maxillary first premolar extraction, complete permanent dentition, CS5/CS6 maturation, and no prior orthodontic treatment.
✕Probably not a fit
Patients with medical exclusions such as diabetes, bleeding disorders, smoking, pregnancy, or other conditions affecting tooth movement may not experience benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study uses a split-mouth design to compare two photobiomodulation methods during maxillary canine retraction in fixed orthodontic treatment. Each participant receives both diode laser and LED treatments on opposite canines at 4-week intervals over 16 weeks, with standardized mechanics guiding retraction. Dental scans track cumulative movement, while patient-reported and clinical outcomes include pain levels. Pulp oxygen saturation (SpO₂) is measured baseline and at several follow-up times to explore changes in pulpal oxygenation related to the interventions. The trial aims to determine if diode laser photobiomodulation offers advantages over LED in speed of movement and pulpal health.
Why it matters
Potential benefit: If successful, diode laser photobiomodulation could accelerate canine retraction and improve patient comfort during orthodontic treatment.
How similar studies have gone: Previous research in photobiomodulation for orthodontic movement has shown variable results; the split-mouth within-subject design is commonly used to mitigate inter-individual differences.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with complete permanent dentition and cervical vertebral maturation at CS5 or CS6 according to the Baccetti classification. * Angle Class I malocclusion. * Indication for fixed orthodontic treatment requiring bilateral extraction of the maxillary first premolars. * Similar position, morphology, and dimensions of the maxillary canines on both sides. * No previous orthodontic treatment. * Willingness to participate in the study and provision of informed consent. Exclusion Criteria: * Patients with bleeding or coagulation disorders, diabetes mellitus, bone diseases, or periodontal diseases. * Use of medications that may affect orthodontic tooth movement or coagulation, including aspirin, heparin, warfarin, nonsteroidal anti-inflammatory drugs, or glucocorticoids. * History of maxillofacial trauma or craniofacial anomalies. * Smoking. * Pregnancy. * Requirement for extraction of teeth other than the first premolars.
Where it's running
-
Saigon Dental Clinic - Dr. Lam
Can Tho, Vietnam Recruiting
Study contacts
- Study coordinator: Lam Le
- Email: lenguyenlam@ctump.edu.vn
- Phone: +84 918130809
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.