3D-printed fixed twin block versus MARA to help correct an underdeveloped lower jaw in Class II malocclusion

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, parallel-group controlled trial enrolling 60 preadolescent patients with Class II malocclusion due to mandibular retrusion, randomized 1:1:1 into three groups. Participants will receive either a CAD/CAM 3D-printed fixed twin block, a MARA appliance, or serve in a comparator group, with dentoskeletal outcomes tracked over the treatment period. Outcomes will include dental and skeletal measurements (likely cephalometric analyses) to quantify changes in jaw position and tooth relationships. Eligibility focuses on circumpubertal growth patients (CVMI 2–4) with overjet ≥ 6 mm and minimal mandibular crowding.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Skeletal Class II malocclusion due to mandibular retrusion.
2. Overjet ≥ 6.0 mm.
3. Normal or low-angle growth pattern.
4. Minimum crowding in the mandibular arch.
5. Undergoing circumpubertal phase of skeletal development (CVMI 2, 3, and 4)

Exclusion Criteria:

1. Clinical signs and symptoms of temporomandibular disorder.
2. Systemic disease affecting bone and general growth.
3. Previous orthodontic treatment
4. Cleft lip or palate.
5. Congenital craniofacial deformity.
6. Abnormal oral habits.

Where it's running

• Faculty of dentistry, Mansoura university
  Al Mansurah, Dakahlia Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Yasmin s Ghaly, phd
• Email: yasminghaly@mans.edu.eg
• Phone: +201065152020

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Comparing clear aligners and fixed braces for treating mild Class II malocclusion in adults

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.