Using Invisalign with special blocks for jaw advancement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the comfort and fit of Invisalign aligners that incorporate occlusal blocks for mandibular advancement. Participants will be monitored for their engagement with the blocks while undergoing treatment for Class II malocclusion and related conditions. The study focuses on assessing how well these aligners perform in improving jaw alignment and overall dental health. The methodology involves direct observation and feedback from participants throughout the treatment process.

Why it matters

Who can join: the full rules

Inclusion Criteria:

• Subject must be eligible for Invisalign treatment with mandibular advancement

Exclusion Criteria:

* Subject's dentition not compatible with device or allergy to device materials
* Subject who is pregnant, has active caries, periodontal disease, TMD, root resorption, has HAE (hereditary angioedema), has been diagnosed with epilepsy or any other seizure disorder

Where it's running

• Astra Orthodontics
  Richmond, British Columbia, Canada Recruiting
• MacKenzie Orthodontics
  Saint John, New Brunswick, Canada Recruiting
• Discover Orthodontics
  Brampton, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Allison Mossing
• Email: amossing@aligntech.com
• Phone: 4083940304

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Maxillary Arch Distalization Using Infrazygomatic Crest Miniscrews for Class II Malocclusion

  This study tests if moving the upper dental arch backward with infrazygomatic crest miniscrews safely corrects Class II malocclusion without extra patient cooperation.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07875660

• Custom-made versus ready-made Carriere Motion appliance for correcting Class II bite

  This study will test whether a custom-made Carriere Motion appliance works better than a ready-made version to correct Class II malocclusion in 12–15-year-olds with permanent teeth.

  Recruiting Mansoura University · Al Mansurah, Adakhlia · NCT07361172

• 3D-printed fixed twin block versus MARA to help correct an underdeveloped lower jaw in Class II malocclusion

  This research will test whether a CAD/CAM 3D-printed fixed twin block or a MARA appliance better improves dental alignment and jaw relationships in preadolescents with Class II due to a small lower jaw.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07340242

• Distalizing upper first and second molars with a palate miniscrew device versus clear aligners

  This trial will test whether a miniscrew‑supported palate device (AMDA®) or clear aligners with Class II elastics moves upper first and second molars back more effectively in people with bilateral Class II malocclusion who need molar distalization.

  Recruiting Aristotle University Of Thessaloniki · Thessaloniki · NCT07040176

• Comparing clear aligners and fixed braces for treating mild Class II malocclusion in adults

  This study is testing whether clear aligners or traditional braces work better for adults with mild Class II malocclusion to improve their teeth and bite.

  Recruiting Hama University · Hama, Hama Governorate · NCT05684510

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.