Respiratory Physiotherapy in Critically Ill Pneumonia Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study follows adults with pneumonia in the ICU to see if a protocolized respiratory physiotherapy program affects levels of inflammatory biomarkers like procalcitonin and CRP. It compares patients receiving structured physiotherapy to a historical control group receiving standard care, focusing on biomarker trajectories and ICU length of stay. Safety of the physiotherapy sessions is also monitored, including events such as desaturation or hemodynamic changes. The analysis will describe changes over time and potential associations with clinical outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Consecutive adult patients (age \>= 18 years at the time of admission).
* Confirmed diagnosis of pneumonia (community-acquired, hospital-acquired, or ventilator-associated pneumonia) as the primary cause of ICU admission or critical complication.
* Anticipated or actual ICU length of stay \>= 48 hours.

Exclusion Criteria:

* Presence of limitation of medical treatment orders or exclusively palliative management upon admission.
* Concomitant severe non-infectious systemic inflammatory diseases that massively alter or mask procalcitonin response (e.g., severe acute pancreatitis, extensive burns).
* Refractory hemodynamic instability or uncontrolled septic shock with escalating vasopressor requirements that contraindicate physical manipulation.

Where it's running

• Hospital H+ Querétaro, Santiago de Querétaro, Querétaro
  Querétaro, Mexico Recruiting

Study contacts

• Study coordinator: Laura Raquel Treviño Rocha
• Email: lauratvrocha@gmail.com
• Phone: 442 111 7104

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.