Evaluating follow-up care for ICU survivors and their caregivers

Improving Medical and Psychological Outcomes After Discharge - Feasibility Study for a Pragmatic, Mixed-methods, Open-label Randomized Controlled Trial Examining the Effectiveness of a Follow-up Clinic for ICU Survivors and Caregivers

Not applicable Interventional Queen's University · NCT06681649

This study tests whether special follow-up care can help ICU survivors and their caregivers recover better than regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorQueen's University Academic / other
Locations1 site (Kingston, Ontario)
Trial IDNCT06681649 on ClinicalTrials.gov

What this trial studies

This trial assesses the effectiveness of specialized follow-up care for ICU survivors and their caregivers compared to standard care. Approximately 80% of ICU survivors face long-term cognitive, physical, and psychiatric challenges, while caregivers also suffer psychosocial effects. The intervention includes follow-up appointments, informational resources, and journaling tools to support recovery. The study employs a pragmatic, mixed-methods approach, utilizing both quantitative clinical assessments and qualitative focus groups to gather comprehensive insights on recovery experiences.

Who should consider this trial

Good fit: Ideal candidates include adult ICU survivors at high risk for long-term complications and their informal caregivers.

Not a fit: Patients who do not have access to a primary care physician or those with a life expectancy of less than six months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve the long-term outcomes and quality of life for ICU survivors and their caregivers.

How similar studies have performed: Other studies have indicated that follow-up care can improve outcomes for ICU survivors, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria - ICU survivors

1. Adult patients (age greater than or equal to 18 years)
2. Life expectancy greater than or equal to 6 months as determined by the attending physician
3. High risk for long-term functional sequelae following ICU discharge, defined as ICU stay greater than or equal to 4 days, or involving at least one of:

   * mechanical ventilation (any, i.e., invasive or non-invasive)
   * tracheostomy
   * delirium (defined as Confusion Assessment Method (CAM) positive or documented history of delirium in the patient's medical record by the clinical care team at some point during their ICU admission)
   * lack of access to a primary care physician for clinical follow-up
   * access to email or mail to complete follow-up questionnaires
   * presence of an informal caregiver

Inclusion criteria - Caregivers

1. Informal caregiver (e.g., spouse, offspring) for ICU survivor as defined above
2. Adult (age greater than or equal to 18 years)

Exclusion criteria - ICU survivors and caregivers

* Neurological or communication difficulties which would preclude completion of follow-up assessments or participation in focus groups
* Inability to speak or read English (required for completion of standardized questionnaires, clinical assessments, and for participation in focus groups)
* Failure to provide consent/failure to have consent provided by a substitute decision maker

Where this trial is running

Kingston, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Critical IllnessDelirium in the Intensive Care Unitcritical illnessdeliriumpost-intensive care syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.