Detecting brain activity changes after traumatic brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the use of depth electrodes to record electrocorticogram (ECoG) data during the placement of an External Ventricular Drain (EVD) in patients with traumatic brain injury (TBI). The goal is to develop a novel algorithm to detect Cortical Spreading Depolarization (CSD) and understand its relationship with imaging findings. By analyzing these recordings, researchers aim to improve diagnosis and treatment strategies for secondary injuries associated with TBI. The approach involves minimal modification to standard surgical procedures, ensuring patient safety and comfort.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient recommended to undergo EVD placement for the monitoring and possible treatment of Intracranial pressure (ICP) after TBI

Exclusion Criteria:

* Contaminated scalp lacerations
* Known systemic infection
* Non-English speaking
* Fixed, uncorrectable coagulopathy

Where it's running

• Hennepin County Medical Center
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: David Darrow, MD — University of Minnesota
• Study coordinator: David Darrow, MD
• Email: rnl@umn.edu
• Phone: 612-624-6666

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Can a bedside brain scan (fNIRS) detect activity in healthy people and in people with disorders of consciousness

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• Long-lasting effects of hyperbaric oxygen therapy on thinking after traumatic brain injury

  This project will see if people with traumatic brain injury who completed a course of hyperbaric oxygen therapy 1–4 years ago still have improved thinking and memory.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.