Community-based eye screening program to prevent blindness
Official title: Village-Integrated Eye Worker Trial II (VIEW II):A Cluster-randomized Trial of the Effectiveness of Community-based Ocular Disease Screening
Run by University of California, San Francisco · NCT03752840 · Data updated 2026-11-12
This study is testing whether a community eye screening program in Nepal can help prevent avoidable blindness by catching eye problems early.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 60200 (estimated) |
| Sponsor | University of California, San Francisco Academic / other |
| Locations | 1 site (San Francisco, California) |
| Status | Recruiting |
| Started | April 21, 2019 |
| Main results expected | August 31, 2029 |
| Study ends | August 31, 2029 |
| Registry record updated | June 9, 2026 |
| Trial ID | NCT03752840 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are community residents aged 50 years and older who are accessible to the participating eye hospitals.
✕Probably not a fit
Patients who are unwilling to participate or live outside the catchment area of the eye hospitals may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial aims to evaluate the effectiveness of an intensive eye screening program in Nepal to prevent avoidable blindness caused by conditions such as age-related macular degeneration, diabetic retinopathy, and glaucoma. The study will involve a large cluster-randomized design where communities will receive visual acuity screenings, with half also undergoing advanced screening techniques like optical coherence tomography and fundus photography. Participants with abnormal results will be referred for further examination and treatment, and visual acuity will be reassessed after nine years to determine the program's impact on visual health outcomes.
Why it matters
Potential benefit: If successful, this program could significantly reduce the incidence of visual impairment and improve overall eye health in at-risk populations.
How similar studies have gone: Other studies have shown success with community-based screening programs for eye diseases, indicating that this approach is promising and not entirely novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Community level Inclusion Criteria: * Located in catchment area of Bharatpur Eye Hospital or Lumbini Eye Institute * Reachable by non-4WD vehicle * Urban or peri-urban Exclusion Criteria: \- Local leaders unwilling to participate Person level Inclusion Criteria: * 60 years and older * Residing in the community during the time of the census Exclusion Criteria: \- Unwilling to participate
Where it's running
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University of California, San Francisco
San Francisco, California, United States Recruiting
Study contacts
- Principal investigator: Jeremy Keenan — University of California, San Francisco
- Study coordinator: Krisianne M Aromin, BS
- Email: krisianne.aromin@ucsf.edu
- Phone: (415) 476-1442
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.