Blood flow restriction training for knee osteoarthritis
Official title: The Impact of Blood-flow-restricted Exercise Training and Pain Education on Pain, Function, Muscle Thickness, and Self-satisfaction in Patients With Knee Osteoarthritis.
Run by University of Hail · NCT07590323 · Data updated 2026-11-12
A personalized program using blood flow restriction and standard care to see if it helps adults with knee osteoarthritis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 70 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | University of Hail Academic / other |
| Locations | 1 site (Ha'il, Ha'il Region) |
| Status | Recruiting |
| Started | June 15, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | September 10, 2026 |
| Trial ID | NCT07590323 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 40 and older with unilateral knee OA (Kellgren-Lawrence grade 2 or 3) willing to participate in 8 weeks of supervised sessions.
✕Probably not a fit
Patients with significant vascular or systemic conditions or those unable to complete the exercise program may not experience benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study tests whether adding blood flow restriction training to standard knee care can improve pain and function in adults with unilateral knee OA. Eligible participants are adults 40 years and older with Kellgren-Lawrence grade 2 or 3 OA, recruited from the University of Hail. Participants attend three supervised sessions per week for eight weeks and will also receive education on pain neuroscience and standard treatments. The study focuses on safety, feasibility, and preliminary signals of benefit in real-world clinical practice.
Why it matters
Potential benefit: If successful, participants may experience reduced knee pain and improved function allowing for better daily activities.
How similar studies have gone: Previous work with blood flow restriction has shown promise in musculoskeletal pain and strength gains, but OA-specific data remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female Age ≥ 40years. * Clinical and radiographic diagnosis of unilateral knee osteoarthritis KOA (Kellgren-Lawrence grade 2, or 3). * Willing to attend 3 supervised sessions/week for 8 weeks. * Able to provide informed consent. Exclusion Criteria: * Peripheral vascular disease, active cancer, lower limb infection, open wound * history of intra-articular injections within the last 3 months * medical condition that may affect their ability to perform exercise (uncontrolled cardiovascular, or neurological disorders) * cognitive and psychiatric disorders
Where it's running
-
University of Hail
Ha'il, Ha'il Region, Saudi Arabia Recruiting
Study contacts
- Study coordinator: Hisham Hussein, PhD
- Email: hm.hussein@uoh.edu.sa
- Phone: +20543704108
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.