Clinical trial Recruiting at 1 site Interventional Ages 40 to 70

Blood flow restriction training for knee osteoarthritis

Official title: The Impact of Blood-flow-restricted Exercise Training and Pain Education on Pain, Function, Muscle Thickness, and Self-satisfaction in Patients With Knee Osteoarthritis.

Run by University of Hail · NCT07590323 · Data updated 2026-11-12

A personalized program using blood flow restriction and standard care to see if it helps adults with knee osteoarthritis.

Quick facts

Study typeInterventional
Ages40 Years to 70 Years
SexAll
Enrollment90 (estimated)
SponsorUniversity of Hail
Academic / other
Locations1 site (Ha'il, Ha'il Region)
StatusRecruiting
StartedJune 15, 2026
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedSeptember 10, 2026
Trial IDNCT07590323 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 40 and older with unilateral knee OA (Kellgren-Lawrence grade 2 or 3) willing to participate in 8 weeks of supervised sessions.

Probably not a fit

Patients with significant vascular or systemic conditions or those unable to complete the exercise program may not experience benefits.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study tests whether adding blood flow restriction training to standard knee care can improve pain and function in adults with unilateral knee OA. Eligible participants are adults 40 years and older with Kellgren-Lawrence grade 2 or 3 OA, recruited from the University of Hail. Participants attend three supervised sessions per week for eight weeks and will also receive education on pain neuroscience and standard treatments. The study focuses on safety, feasibility, and preliminary signals of benefit in real-world clinical practice.

Why it matters

Potential benefit: If successful, participants may experience reduced knee pain and improved function allowing for better daily activities.

How similar studies have gone: Previous work with blood flow restriction has shown promise in musculoskeletal pain and strength gains, but OA-specific data remain limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male and female Age ≥ 40years.
* Clinical and radiographic diagnosis of unilateral knee osteoarthritis KOA (Kellgren-Lawrence grade 2, or 3).
* Willing to attend 3 supervised sessions/week for 8 weeks.
* Able to provide informed consent.

Exclusion Criteria:

* Peripheral vascular disease, active cancer, lower limb infection, open wound
* history of intra-articular injections within the last 3 months
* medical condition that may affect their ability to perform exercise (uncontrolled cardiovascular, or neurological disorders)
* cognitive and psychiatric disorders

Where it's running

  • University of Hail
    Ha'il, Ha'il Region, Saudi Arabia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.