Analyzing genetic factors affecting pain after surgery
Genetic Variants and Postoperative Pain
This study is trying to see if certain genes can help explain why some people have more pain after surgery than others, to improve pain management for those patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 1 site (Bern) |
| Trial ID | NCT03489499 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between genetic variants and postoperative pain outcomes in patients undergoing elective surgery. It will collect data on clinical, patient-related, surgery-related, and anesthesia-related variables, alongside genetic information, to identify potential associations with severe acute pain and chronic postsurgical pain. By understanding these factors, the study seeks to improve pain management strategies for surgical patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 years and older who are scheduled for elective surgery and can provide informed consent.
Not a fit: Patients with cognitive impairments or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized pain management approaches based on genetic profiles, improving recovery experiences for patients.
How similar studies have performed: While there have been studies exploring genetic factors in pain management, this specific approach focusing on postoperative pain outcomes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years and older * Written informed consent * Elective surgery * Patients' ability to understand the purpose of the study Exclusion Criteria * No informed consent * Cognitive impairment
Where this trial is running
Bern
- Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern — Bern, Switzerland (Recruiting)
Study contacts
- Principal investigator: Ulrike M Stamer, MD — Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
- Study coordinator: Ulrike M Stamer, Prof. MD
- Email: ulrike.stamer@dbmr.unibe.ch
- Phone: 0041-316329995
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.