Clinical trial Recruiting at 1 site Observational Ages 18 and up

Analyzing genetic factors affecting pain after surgery

Official title: Genetic Variants and Postoperative Pain

Run by Insel Gruppe AG, University Hospital Bern · NCT03489499 · Data updated 2026-11-12

This study is trying to see if certain genes can help explain why some people have more pain after surgery than others, to improve pain management for those patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorInsel Gruppe AG, University Hospital Bern
Academic / other
Locations1 site (Bern)
StatusRecruiting
StartedJanuary 2, 2011
Main results expectedDecember 2026
Study endsApril 2027
Registry record updatedJanuary 7, 2026
Trial IDNCT03489499 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 years and older who are scheduled for elective surgery and can provide informed consent.

Probably not a fit

Patients with cognitive impairments or those unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between genetic variants and postoperative pain outcomes in patients undergoing elective surgery. It will collect data on clinical, patient-related, surgery-related, and anesthesia-related variables, alongside genetic information, to identify potential associations with severe acute pain and chronic postsurgical pain. By understanding these factors, the study seeks to improve pain management strategies for surgical patients.

Why it matters

Potential benefit: If successful, this study could lead to personalized pain management approaches based on genetic profiles, improving recovery experiences for patients.

How similar studies have gone: While there have been studies exploring genetic factors in pain management, this specific approach focusing on postoperative pain outcomes is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years and older
* Written informed consent
* Elective surgery
* Patients' ability to understand the purpose of the study

Exclusion Criteria

* No informed consent
* Cognitive impairment

Where it's running

  • Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
    Bern, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Ulrike M Stamer, MD — Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
  • Study coordinator: Ulrike M Stamer, Prof. MD
  • Email: ulrike.stamer@dbmr.unibe.ch
  • Phone: 0041-316329995

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.