Analyzing genetic factors affecting pain after surgery
Official title: Genetic Variants and Postoperative Pain
Run by Insel Gruppe AG, University Hospital Bern · NCT03489499 · Data updated 2026-11-12
This study is trying to see if certain genes can help explain why some people have more pain after surgery than others, to improve pain management for those patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 1 site (Bern) |
| Status | Recruiting |
| Started | January 2, 2011 |
| Main results expected | December 2026 |
| Study ends | April 2027 |
| Registry record updated | January 7, 2026 |
| Trial ID | NCT03489499 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 years and older who are scheduled for elective surgery and can provide informed consent.
✕Probably not a fit
Patients with cognitive impairments or those unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between genetic variants and postoperative pain outcomes in patients undergoing elective surgery. It will collect data on clinical, patient-related, surgery-related, and anesthesia-related variables, alongside genetic information, to identify potential associations with severe acute pain and chronic postsurgical pain. By understanding these factors, the study seeks to improve pain management strategies for surgical patients.
Why it matters
Potential benefit: If successful, this study could lead to personalized pain management approaches based on genetic profiles, improving recovery experiences for patients.
How similar studies have gone: While there have been studies exploring genetic factors in pain management, this specific approach focusing on postoperative pain outcomes is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years and older * Written informed consent * Elective surgery * Patients' ability to understand the purpose of the study Exclusion Criteria * No informed consent * Cognitive impairment
Where it's running
-
Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
Bern, Switzerland Recruiting
Study contacts
- Principal investigator: Ulrike M Stamer, MD — Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
- Study coordinator: Ulrike M Stamer, Prof. MD
- Email: ulrike.stamer@dbmr.unibe.ch
- Phone: 0041-316329995
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.