Clinical trial Recruiting at 1 site Observational Ages 18 and up

Analyzing genetic factors affecting surgery outcomes

Official title: Genetic Variants and Perioperative Morbidity and Mortality

Run by Insel Gruppe AG, University Hospital Bern · NCT02124499 · Data updated 2026-11-12

This study is trying to see how genetic differences might affect the recovery and complications people experience after elective surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment20000 (estimated)
SponsorInsel Gruppe AG, University Hospital Bern
Academic / other
Locations1 site (Bern)
StatusRecruiting
StartedJanuary 2, 2011
Main results expectedFebruary 2027
Study endsDecember 2027
Registry record updatedJanuary 7, 2026
Trial IDNCT02124499 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are scheduled for elective surgery and can provide informed consent.

Probably not a fit

Patients with cognitive impairments or those unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the relationship between genetic variants and perioperative outcomes in patients undergoing elective surgery. It will analyze various factors, including patient demographics, surgical details, and genetic backgrounds, to identify those at risk for complications such as postoperative nausea, vomiting, and pain. The study will involve two independent patient cohorts to ensure robust data collection and analysis of intraoperative and postoperative complications.

Why it matters

Potential benefit: If successful, this study could lead to personalized approaches in anesthesia and surgical care, reducing complications and improving recovery for patients.

How similar studies have gone: Other studies have shown promising results in understanding genetic influences on surgical outcomes, suggesting that this approach could yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years and older
* Written informed consent
* Scheduled surgery

Exclusion Criteria

* No informed consent
* Cognitive impairment

Where it's running

  • Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
    Bern, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Ulrike M Stamer, MD — Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
  • Study coordinator: Ulrike M Stamer, Prof. MD
  • Email: ulrike.stamer@dbmr.unibe.ch
  • Phone: 0041-316329995

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.