Analyzing genetic factors affecting surgery outcomes
Official title: Genetic Variants and Perioperative Morbidity and Mortality
Run by Insel Gruppe AG, University Hospital Bern · NCT02124499 · Data updated 2026-11-12
This study is trying to see how genetic differences might affect the recovery and complications people experience after elective surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20000 (estimated) |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 1 site (Bern) |
| Status | Recruiting |
| Started | January 2, 2011 |
| Main results expected | February 2027 |
| Study ends | December 2027 |
| Registry record updated | January 7, 2026 |
| Trial ID | NCT02124499 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are scheduled for elective surgery and can provide informed consent.
✕Probably not a fit
Patients with cognitive impairments or those unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the relationship between genetic variants and perioperative outcomes in patients undergoing elective surgery. It will analyze various factors, including patient demographics, surgical details, and genetic backgrounds, to identify those at risk for complications such as postoperative nausea, vomiting, and pain. The study will involve two independent patient cohorts to ensure robust data collection and analysis of intraoperative and postoperative complications.
Why it matters
Potential benefit: If successful, this study could lead to personalized approaches in anesthesia and surgical care, reducing complications and improving recovery for patients.
How similar studies have gone: Other studies have shown promising results in understanding genetic influences on surgical outcomes, suggesting that this approach could yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years and older * Written informed consent * Scheduled surgery Exclusion Criteria * No informed consent * Cognitive impairment
Where it's running
-
Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
Bern, Switzerland Recruiting
Study contacts
- Principal investigator: Ulrike M Stamer, MD — Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
- Study coordinator: Ulrike M Stamer, Prof. MD
- Email: ulrike.stamer@dbmr.unibe.ch
- Phone: 0041-316329995
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.