Analyzing genetic factors affecting surgery outcomes
Genetic Variants and Perioperative Morbidity and Mortality
This study is trying to see how genetic differences might affect the recovery and complications people experience after elective surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 1 site (Bern) |
| Trial ID | NCT02124499 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the relationship between genetic variants and perioperative outcomes in patients undergoing elective surgery. It will analyze various factors, including patient demographics, surgical details, and genetic backgrounds, to identify those at risk for complications such as postoperative nausea, vomiting, and pain. The study will involve two independent patient cohorts to ensure robust data collection and analysis of intraoperative and postoperative complications.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are scheduled for elective surgery and can provide informed consent.
Not a fit: Patients with cognitive impairments or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to personalized approaches in anesthesia and surgical care, reducing complications and improving recovery for patients.
How similar studies have performed: Other studies have shown promising results in understanding genetic influences on surgical outcomes, suggesting that this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years and older * Written informed consent * Scheduled surgery Exclusion Criteria * No informed consent * Cognitive impairment
Where this trial is running
Bern
- Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern — Bern, Switzerland (Recruiting)
Study contacts
- Principal investigator: Ulrike M Stamer, MD — Department of Anaesthesiology and Pain Medicine, Inselspital, University of Bern
- Study coordinator: Ulrike M Stamer, Prof. MD
- Email: ulrike.stamer@dbmr.unibe.ch
- Phone: 0041-316329995
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.