Clinical trial No longer in our active list Observational Ages 18 and up

AI system for detecting periodontitis in dental images

Official title: What is the Diagnostic Accuracy of a AI-clinical Knowledge Based Hybrid System for the Diagnosis of Stage II-IV Periodontitis Using OPG Images?A Multi-center Study

Run by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · NCT06306677 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing a new AI system to see if it can accurately detect periodontitis in dental X-rays, helping dentists catch this common gum disease earlier.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1200 (estimated)
SponsorShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Academic / other
Locations3 sites (Shanghai, Shanghai and 2 other locations)
Trial IDNCT06306677 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 18 and older who have undergone OPG imaging.

Probably not a fit

Patients with an edentulous mouth will not benefit from this study as they do not have teeth to assess for periodontitis.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the accuracy of an AI-clinical knowledge-based hybrid system in diagnosing periodontitis using orthopantomography (OPG) images. The study compares the AI system's diagnostic performance against human experts for identifying stages II-IV of periodontitis. By utilizing OPG, a widely used dental radiograph, the study seeks to enhance early detection and treatment of periodontitis, which is often overlooked. The research involves collaboration among multiple international centers to gather a diverse set of OPG images for analysis.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and treatment of periodontitis, reducing the risk of severe dental complications.

How similar studies have gone: Other studies have shown promise in using AI for diagnostic purposes in dentistry, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Aged 18 and above
2. Having taken the OPG image

Exclusion Criteria:

1. Edentulous mouth

Where it's running

  • Shanghai Perio-Implant Innovation Center
    Shanghai, Shanghai, China
    Recruiting
  • Prince Philip Dental Hospital
    Hong Kong, Hong Kong
    Recruiting
  • La Sapienza Dental School
    Roma, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.