AI system for detecting periodontitis in dental images

What is the Diagnostic Accuracy of a AI-clinical Knowledge Based Hybrid System for the Diagnosis of Stage II-IV Periodontitis Using OPG Images?A Multi-center Study

Observational Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · NCT06306677

This study is testing a new AI system to see if it can accurately detect periodontitis in dental X-rays, helping dentists catch this common gum disease earlier.

Quick facts

Study typeObservational
Enrollment1200 (estimated)
Ages18 Years and up
SexAll
SponsorShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Academic / other
Locations3 sites (Shanghai, Shanghai and 2 other locations)
Trial IDNCT06306677 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the accuracy of an AI-clinical knowledge-based hybrid system in diagnosing periodontitis using orthopantomography (OPG) images. The study compares the AI system's diagnostic performance against human experts for identifying stages II-IV of periodontitis. By utilizing OPG, a widely used dental radiograph, the study seeks to enhance early detection and treatment of periodontitis, which is often overlooked. The research involves collaboration among multiple international centers to gather a diverse set of OPG images for analysis.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 18 and older who have undergone OPG imaging.

Not a fit: Patients with an edentulous mouth will not benefit from this study as they do not have teeth to assess for periodontitis.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and treatment of periodontitis, reducing the risk of severe dental complications.

How similar studies have performed: Other studies have shown promise in using AI for diagnostic purposes in dentistry, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Aged 18 and above
2. Having taken the OPG image

Exclusion Criteria:

1. Edentulous mouth

Where this trial is running

Shanghai, Shanghai and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PeriodontitisPeriodontal DiseasesArtificial IntelligenceRadiograph
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.