Clinical trial Recruiting at 1 site Observational Ages 18 and up

Candida albicans and periodontitis in Syrian patients

Official title: Prevalence and Impact of Candida Albicans in Syrian Patients With Periodontitis: A Cross-Sectional Study

Run by Al-Hawash Private University · NCT07574827 · Data updated 2026-11-12

This project will test whether Candida albicans is commonly present in the gum pockets of Syrian adults with chronic periodontitis.

More Periodontitis trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorAl-Hawash Private University
Academic / other
Locations1 site (Homs)
StatusRecruiting
StartedApril 7, 2026
Main results expectedMarch 2027
Study endsSeptember 2027
Registry record updatedNovember 4, 2026
Trial IDNCT07574827 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) diagnosed with chronic periodontitis who consent to participate, have no systemic diseases affecting oral health, and have not used antibiotics or antifungals in the past three months.

Probably not a fit

People with systemic conditions that affect oral health (for example diabetes or immunosuppression), or those who recently took antibiotics/antifungals, are excluded and would not benefit from this study's findings for their care.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls adults with clinically diagnosed chronic periodontitis at Al-Hawash Private University in Homs. Participants will receive a standard periodontal exam (attachment loss, probing depth) and samples collected from subgingival pockets. Samples will be cultured, typically on Sabouraud Dextrose Agar, to detect Candida albicans. The study will report the prevalence of Candida in this patient group and explore associations with periodontal measures.

Why it matters

Potential benefit: If Candida albicans is shown to be common or linked to worse periodontal findings, clinicians could consider antifungal-directed strategies or adjusted care to improve outcomes.

How similar studies have gone: Previous studies have detected Candida albicans in periodontal pockets and suggested it may worsen inflammation, but its precise role in periodontitis remains uncertain.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 years and older.
* Diagnosed with chronic periodontitis based on clinical examination (attachment loss, probing depth).
* Consent to participate in the study.

Exclusion Criteria:

* Patients with systemic diseases affecting oral health (e.g., diabetes, immunosuppressive conditions).
* Recent antibiotic or antifungal treatment within the last three months.

Where it's running

  • Al-Hawash Private University, Faculty of Dentistry
    Homs, Syria
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.