Candida albicans and periodontitis in Syrian patients
Prevalence and Impact of Candida Albicans in Syrian Patients With Periodontitis: A Cross-Sectional Study
This project will test whether Candida albicans is commonly present in the gum pockets of Syrian adults with chronic periodontitis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Al-Hawash Private University Academic / other |
| Locations | 1 site (Homs) |
| Trial ID | NCT07574827 on ClinicalTrials.gov |
What this trial studies
This observational study enrolls adults with clinically diagnosed chronic periodontitis at Al-Hawash Private University in Homs. Participants will receive a standard periodontal exam (attachment loss, probing depth) and samples collected from subgingival pockets. Samples will be cultured, typically on Sabouraud Dextrose Agar, to detect Candida albicans. The study will report the prevalence of Candida in this patient group and explore associations with periodontal measures.
Who should consider this trial
Good fit: Adults (18+) diagnosed with chronic periodontitis who consent to participate, have no systemic diseases affecting oral health, and have not used antibiotics or antifungals in the past three months.
Not a fit: People with systemic conditions that affect oral health (for example diabetes or immunosuppression), or those who recently took antibiotics/antifungals, are excluded and would not benefit from this study's findings for their care.
Why it matters
Potential benefit: If Candida albicans is shown to be common or linked to worse periodontal findings, clinicians could consider antifungal-directed strategies or adjusted care to improve outcomes.
How similar studies have performed: Previous studies have detected Candida albicans in periodontal pockets and suggested it may worsen inflammation, but its precise role in periodontitis remains uncertain.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years and older. * Diagnosed with chronic periodontitis based on clinical examination (attachment loss, probing depth). * Consent to participate in the study. Exclusion Criteria: * Patients with systemic diseases affecting oral health (e.g., diabetes, immunosuppressive conditions). * Recent antibiotic or antifungal treatment within the last three months.
Where this trial is running
Homs
- Al-Hawash Private University, Faculty of Dentistry — Homs, Syria (Recruiting)
Study contacts
- Principal investigator: Ali Abou Sulaiman, Ph.D. in Periodontology — Al-Hawash Private University
- Study coordinator: Ali Abou Sulaiman
- Email: dr.ali.abousulaiman@hpu.edu.sy
- Phone: +963956790836
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.