Comparing two surgical methods for treating mandibular deficiency

Evaluating the Efficacy of Vertical Ramus Osteotomy With Iliac Graft Versus Bilateral Sagittal Split Osteotomy for the Correction of Mandibular Deficiency in Skeletal Class II Cases Management. A Randomized Controlled Trial

NA · Fayoum University · NCT06850194

This study is testing which of two surgical methods works better for people with jaw problems caused by mandibular deficiency.

Quick facts

PhaseNA
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorFayoum University (other)
Locations1 site (Beni-seuf, Egypt)
Trial IDNCT06850194 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effectiveness of vertical ramus osteotomy with iliac graft versus bilateral sagittal split osteotomy in patients with mandibular deficiency. A total of 20 patients will be enrolled, with 10 receiving each surgical intervention. Comprehensive clinical examinations and lateral cephalometric radiographic analyses will be conducted at three time points: before surgery, immediately after, and six months post-surgery. The study will utilize standardized imaging and surgical planning techniques to ensure consistency across cases.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old with severe mandibular deficiency classified as skeletal class II.

Not a fit: Patients with chin deviation, severe TMJ symptoms, or those who have had previous mandibular surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into the most effective surgical approach for improving mandibular function and aesthetics in patients with skeletal class II deficiencies.

How similar studies have performed: Previous studies have shown varying success with similar surgical approaches, but this specific comparison is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with age above 18 years old suffered from skeletal class II with severe mandibular deficiency

Exclusion Criteria:

* patients with chin deviation,
* severe temporomandibular joint (TMJ) symptoms.
* Sever periodontal disease
* pregnancy,
* previous mandibular surgery,
* inability to follow-up for the study protocol

Where this trial is running

Beni-seuf, Egypt

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Mandibular Deficiency

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.