Sponsor or institution

Clinical trials and research at VA North Texas Health Care System

• 14NIH research projects

NIH-funded research (14)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Personalized CKD-MBD care using systems biology and AI

  A patient-facing program aims to tailor mineral-balance therapy for people with chronic kidney disease by using a computer model and smart decision rules to predict who will respond best to treatments.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11644324

• Post-COVID Neurocognitive Changes: What We Learn About Veterans

  This study will follow Veterans who had COVID-19 to understand how brain function and thinking skills may be affected over time.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11620617

• Targeting the DC-HIL pathway to treat melanoma

  A new approach aims to block the DC-HIL pathway to help people with melanoma by affecting tumor blood vessels and immune response.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11212795

• Myeloid immune cells that may drive autoimmune damage in the brain and spinal cord

  This project looks at a specific group of immune cells to understand how they might cause or worsen autoimmune attacks in the brain and spinal cord for people with conditions like multiple sclerosis.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11212736

• Blood pressure–guided fluid removal during hemodialysis

  This project uses blood pressure patterns recorded during dialysis to guide how much fluid is removed for people on hemodialysis.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11132726

• Using blood pressure patterns to improve fluid management in dialysis patients

  This study is looking at how keeping an eye on blood pressure during dialysis can help doctors safely remove extra fluid from patients with severe kidney disease, especially veterans, to make their treatment safer and improve their health.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11056677

• Investigating how MIF-CD74 signaling affects immune responses in pancreatic cancer.

  This study is looking at how certain immune cells in pancreatic cancer might be holding back the body's ability to fight the disease, and it hopes to find new ways to boost the immune response to help patients with this tough cancer.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11052061

• Understanding and managing bone and mineral disorders in chronic kidney disease

  This study is looking at how chronic kidney disease affects important minerals in your body, like phosphate and calcium, and aims to find better ways to treat these issues by using advanced technology to personalize care just for you.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11043305

• Improving physical activity and mental health in older veterans with pain and depression

  This study is looking at how a special program called MOTIVATE can help older veterans who are dealing with pain and depression by encouraging them to be more active and set personal goals, all with the support of a health coach over 12 weeks, to help them feel better and enjoy life more.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11006245

• Using remote ischemic preconditioning to protect the kidneys and heart in heart failure patients

  This study is looking at a special technique that might help protect your kidneys and heart during certain medical procedures that use contrast dye, especially if you have heart failure or coronary artery disease. By briefly restricting blood flow to a limb, we hope to improve blood flow and reduce the risk of kidney d

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-10980505

• Investigating a new pathway to treat melanoma and other cancers

  This study is looking at a new way to help treat melanoma by understanding how a specific part of the immune system and blood vessels work together, with the hope of creating better treatments for melanoma and possibly other cancers.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-10950325

• Investigating specific immune cells involved in brain autoimmune diseases

  This study is looking at a special type of immune cell to see how it might play a role in autoimmune diseases that affect the brain and nervous system, with the hope of finding new ways to help patients like you.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-10948901

• How the immune system responds to heart injury and inflammation

  This study is looking at how the immune system reacts to heart injuries caused by reduced blood flow, and it aims to find new ways to help the heart heal better by understanding how certain signals from damaged heart cells can cause inflammation.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-10871801

• Investigating the long-term brain effects of COVID-19

  This study is looking at how COVID-19 might affect thinking and memory in Veterans, and it wants to find out if certain treatments can help protect their brains as they recover from the virus.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-10807683

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