Investigating the long-term brain effects of COVID-19
Official title: Characteristics and Determinants of Post-COVID Neurocognitive Dysfunction
Funded at VA North Texas Health Care System · NIH-10807683 · Data updated 2026-11-12
This study is looking at how COVID-19 might affect thinking and memory in Veterans, and it wants to find out if certain treatments can help protect their brains as they recover from the virus.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA North Texas Health Care System NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| NIH project number | 1I01CX002739-01 |
| Project ID | NIH-10807683 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recovered from COVID-19 and are experiencing neurocognitive symptoms.
✕Less likely to help
Patients who have not had COVID-19 or do not exhibit any cognitive symptoms may not benefit from this research.
What this research studies
This research focuses on understanding the neurocognitive dysfunction that can occur after COVID-19 infection, particularly among Veterans. It aims to identify the characteristics and determinants of these cognitive changes, exploring potential mechanisms of neuronal damage caused by the virus. The study will utilize a well-characterized cohort to evaluate biomarkers and imaging evidence related to inflammation and neuronal damage. Additionally, it will investigate whether antiviral treatments can help prevent cognitive impairment in patients recovering from COVID-19.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential treatments for cognitive impairments resulting from COVID-19.
How similar studies have gone: While some preliminary studies have explored cognitive effects post-COVID, this research aims to provide a more comprehensive evaluation and is considered novel in its approach.
Where this research is happening
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VA North Texas Health Care System
Dallas, United States Active
Researchers
- Principal investigator: Bedimo, Roger — VA North Texas Health Care System
- Study coordinator: Bedimo, Roger
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.