Understanding and managing bone and mineral disorders in chronic kidney disease
Systems Biology Approach to the Management of Chronic Kidney Disease-Mineral Bone Disorder
This study is looking at how chronic kidney disease affects important minerals in your body, like phosphate and calcium, and aims to find better ways to treat these issues by using advanced technology to personalize care just for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA North Texas Health Care System NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11043305 on NIH RePORTER |
What this research studies
This research investigates how chronic kidney disease (CKD) affects mineral metabolism, particularly focusing on phosphate, calcium, and parathyroid hormone levels. It aims to improve patient outcomes by using a systems biology approach combined with artificial intelligence to tailor treatments based on individual responses. By identifying distinct phenotypic subsets of CKD-Mineral Bone Disorder (MBD), the research seeks to optimize therapeutic strategies for better management of these conditions. The study emphasizes the importance of personalized medicine in addressing the complexities of CKD-MBD.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans suffering from chronic kidney disease who are experiencing complications related to mineral metabolism.
Not a fit: Patients with chronic kidney disease who do not have significant mineral metabolism issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of bone and mineral disorders in CKD patients, potentially reducing cardiovascular risks and enhancing survival rates.
How similar studies have performed: Previous research has shown promise in using systems biology and artificial intelligence to improve treatment outcomes in complex medical conditions, suggesting potential for success in this approach.
Where this research is happening
Dallas, United States
- VA North Texas Health Care System — Dallas, United States (Active)
Researchers
- Principal investigator: Lederer, Eleanor D — VA North Texas Health Care System
- Study coordinator: Lederer, Eleanor D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.