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Clinical trials and research at University of Michigan Rogel Cancer Center

• 40Clinical trials
• 1New in 30 days
• 3Countries

Newest trials

All recruiting trials (40)

• Natalizumab to help prevent brain-related side effects during CAR-T therapy in certain lymphoma patients

  This phase 2 study tests whether natalizumab can reduce severe ICANS in adults with recurrent or refractory DLBCL or MCL receiving CAR-T therapy.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07892027

• AI-powered supportive care chatbot for young adult cancer survivors

  A chatbot driven by artificial intelligence is tested to help young adult cancer survivors manage symptoms and care needs after treatment.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07772596

• Non-invasive brain stimulation to help chemotherapy-induced nerve problems in cancer survivors

  This trial tests whether a gentle brain stimulation method (tDCS) can help reduce numbness, tingling, and pain from CIPN in cancer survivors who are not currently in treatment.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07673614

• Targeted Early Detection for Men at High Genetic Risk for Prostate Cancer

  This study tests urinary biomarkers and PSA to see if they can improve early detection for men with a strong family or genetic risk for prostate cancer.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07645391

• Office-based ureteroscopy using a single-use digital flexible ureteroscope for upper tract urothelial carcinoma

  This trial tests whether performing awake ureteroscopy in a doctor’s office, instead of an operating room, can accurately assess upper tract urothelial carcinoma in adults.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07630155

• Pomalidomide after CAR T-cell therapy for relapsed or refractory CD19+ B-cell leukemia or lymphoma

  This phase 1 study tests whether pomalidomide, given after CD19 CAR T-cell therapy, is safe and may help people whose CD19+ B-cell leukemia or lymphoma has come back or not responded.

  Recruiting Phase 1 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07532525

• Urine and MRI approach to find aggressive prostate cancer early

  This study tests whether a urine test called MPS2, paired with MRI, can better detect aggressive prostate cancer in men 50–75 at risk, possibly reducing unnecessary biopsies.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07526545

• Resistant potato starch to reduce joint and muscle symptoms in people starting aromatase inhibitors for early-stage or high-risk breast cancer

  This phase II trial will test whether taking resistant potato starch can reduce joint pain and stiffness in people with stage 0–III or high-risk breast cancer who are starting aromatase inhibitor therapy.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07443943

• Virtual LASO-3 diet program to ease chemotherapy-related numbness and tingling

  This trial tests whether a virtual diet program that lowers added sugar and increases fiber and omega-3s can help cancer survivors who have numbness, tingling, or pain after neurotoxic chemotherapy.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07365007

• Leuprolide versus goserelin to stop ovarian estrogen production in pre- or peri-menopausal women with breast cancer

  This study tests whether two doses of leuprolide or goserelin better stops the ovaries from making estrogen in pre- or peri-menopausal women with breast cancer.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07158021

• PET/CT imaging with [68Ga] Ga-FAPI-04 for people with high-grade neuroendocrine cancer

  This will test if a PET/CT scan using [68Ga] Ga-FAPI-04 can find high-grade neuroendocrine cancer in adults.

  Recruiting Early Phase 1 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07132645

• Personalized neck radiation guided by sentinel lymph node biopsy for oral cavity cancer

  This phase II trial sees if using sentinel lymph node biopsy to guide which side(s) of the neck get radiation can safely reduce unnecessary radiation for people with oral cavity squamous cell carcinoma.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07121595

• SPECT/CT imaging to measure radiation dose during Pluvicto (177Lu‑PSMA‑617) treatment

  This project will use SPECT/CT scans to see if measured radiation doses to tumors and normal organs predict response and side effects in men with metastatic castration‑resistant prostate cancer receiving 177Lu‑PSMA‑617 (Pluvicto).

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07096999

• Ivonescimab given before surgery for resectable stage II–IV head and neck cancer

  This trial tests whether giving ivonescimab before surgery helps people with resectable stage II–IV head and neck squamous cell carcinoma.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT07094685

• Virtual solution-focused brief therapy for emotional distress in adolescent and young adult cancer survivors

  This project tests whether short, virtual solution-focused therapy helps adolescents and young adults (ages 15–39) who are cancer survivors reduce anxiety and depression compared with enhanced usual care.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06941324

• Helping families share hereditary cancer risk information and access genetic testing

  This project tries web-based navigation and communication tools to help adults with a known hereditary cancer gene and their adult biological relatives share risk information and make it easier for relatives to get genetic testing.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06927947

• A decision aid to help breast cancer patients make chemotherapy choices

  This study tests a smartphone tool to help breast cancer patients who have nerve pain from chemotherapy make better choices about their treatment.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06915168

• Virus-based gene therapy with valacyclovir for resectable recurrent malignant brain tumors in children and young adults

  This trial tries two virus-delivered genes plus the oral antiviral valacyclovir to see if the approach is safe and tolerable for children and young adults whose malignant brain tumors have returned and can be surgically removed.

  Recruiting Phase 1 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06914479

• Inulin gel plus ipilimumab and nivolumab for advanced kidney (renal cell) cancer

  This trial tests whether adding an inulin gel to the immunotherapy drugs ipilimumab and nivolumab helps people with locally advanced or metastatic clear cell or sarcomatoid renal cell carcinoma.

  Recruiting Phase 1/2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06866262

• Resistant potato starch plus iron chelation to reduce complications after allogeneic stem cell transplant

  This Phase II trial will test whether taking resistant potato starch together with the iron chelator deferasirox around an allogeneic stem cell transplant can lower acute graft‑versus‑host disease and improve graft‑versus‑host disease/relapse‑free survival for adult transplant recipients.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06784336

• Personalized home treadmill exercise for people with Familial Adenomatous Polyposis (FAP)

  This trial will try different amounts of home treadmill exercise in people with FAP who have at least five rectal polyps to see if exercise can help prevent polyps from coming back.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan and 1 other locations · NCT06641310

• Combining ruxolitinib and enzalutamide for advanced prostate cancer treatment

  This study is testing if combining two medications, ruxolitinib and enzalutamide, can safely help men with advanced prostate cancer that hasn't responded to hormone therapy.

  Recruiting Phase 1/2 University of Michigan Rogel Cancer Center · Chicago, Illinois and 2 other locations · NCT06616155

• Neoadjuvant enfortumab vedotin plus pembrolizumab for cisplatin-eligible upper tract urothelial cancer

  This trial tests whether giving enfortumab vedotin with pembrolizumab before surgery helps people with high-grade, cisplatin-eligible upper tract urothelial cancer.

  Recruiting at 2 sites Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan and 1 other locations · NCT06356155

• Using gilteritinib to treat advanced ALK positive lung cancer

  This study is testing if gilteritinib can safely help people with advanced ALK positive lung cancer who haven't had success with other treatments.

  Recruiting Phase 1 University of Michigan Rogel Cancer Center · Los Angeles, California and 2 other locations · NCT06225427

• Exercise program for Black breast cancer survivors

  This study tests whether a personalized 12-week exercise program can help Black breast cancer survivors become more active compared to a health education group.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06100263

• Counseling program for lymphoma survivors to reduce fatigue

  This study is testing if a special counseling program about diet can help lymphoma survivors who are feeling very tired to feel better and improve their quality of life.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT06047626

• Assessing prostate cancer tissue using a fine needle probe

  This study is testing a new fine needle probe that uses light and sound to check for prostate cancer without taking tissue samples during biopsies.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05965180

• Combining pembrolizumab and mogamulizumab for advanced cutaneous T-cell lymphomas

  This study is testing if combining two drugs, pembrolizumab and mogamulizumab, can help people with advanced cutaneous T-cell lymphomas that haven't responded to other treatments.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05956041

• Program to enhance heart health in patients getting stem cell transplants

  This study tests a heart health program for patients with cardiovascular risks who are getting stem cell transplants to see if it helps them get fitter and avoid heart problems.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05945121

• Using Prednisone to Protect the Liver During Radiation Therapy for Liver Cancer

  This study is testing if taking Prednisone before and during radiation therapy can help protect the liver in patients with liver cancer.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05901519

• Personalized treatment for early-stage p16+ oropharyngeal cancer

  This study is testing two personalized treatment options for people with early-stage p16+ oropharyngeal cancer to see which one works best and is safer.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05894083

• Using parametric response mapping to detect lung injury in transplant patients

  This study is testing if a new imaging method can help predict lung problems in transplant patients who have chronic graft versus host disease or chronic lung disease.

  Recruiting at 3 sites University of Michigan Rogel Cancer Center · Stanford, California and 5 other locations · NCT05866302

• Biomarker analysis for metastatic leiomyosarcoma patients

  This study is trying to see if blood and tissue samples can help find markers that show how well chemotherapy is working for patients with advanced leiomyosarcoma.

  Recruiting at 11 sites University of Michigan Rogel Cancer Center · Santa Monica, California and 10 other locations · NCT05653388

• Comparing Paclitaxel Infusion Durations in Cancer Patients with Low Muscle Mass

  This study is testing if giving paclitaxel over a longer time helps cancer patients with low muscle mass have better drug levels in their system compared to those with normal muscle mass.

  Recruiting Phase 4 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05183126

• Comparing two types of radiation therapy for prostate cancer after surgery

  This study is testing whether a shorter, five-session radiation therapy for prostate cancer after surgery helps patients feel better compared to a longer treatment that takes several weeks.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT05038332

• Biomarker study for localized leiomyosarcoma

  This study is testing if a blood test for tumor DNA can help predict how well chemotherapy works for people with localized leiomyosarcoma who are at high risk of their cancer spreading after surgery.

  Recruiting at 3 sites University of Michigan Rogel Cancer Center · Ann Arbor, Michigan and 2 other locations · NCT04925089

• Using pacritinib to treat relapsed or refractory T-cell lymphoproliferative neoplasms

  This study is testing if the oral medication pacritinib can help people with certain types of T-cell lymphomas that have come back or didn’t respond to other treatments.

  Recruiting at 4 sites Phase 2 University of Michigan Rogel Cancer Center · Duarte, California and 5 other locations · NCT04858256

• Using Cyclophosphamide and Sirolimus to treat advanced thyroid cancer

  This study is testing if a combination of two medications, Cyclophosphamide and Sirolimus, can help people with advanced thyroid cancer that hasn't responded to other treatments.

  Recruiting Phase 2 University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT03099356

• Using MRI to assess myelofibrosis

  This study is testing if special MRI scans can help doctors see how severe myelofibrosis is and how well treatments are working for patients.

  Recruiting University of Michigan Rogel Cancer Center · Ann Arbor, Michigan · NCT01973881

• Using stool and blood tests to detect colorectal cancer early

  This study is testing if stool and blood tests can help find colorectal cancer and polyps earlier than regular colonoscopies for people at risk.

  Recruiting at 9 sites University of Michigan Rogel Cancer Center · Los Angeles, California and 12 other locations · NCT00843375

Quick answers

How many clinical trials run by University of Michigan Rogel Cancer Center are recruiting right now?

40, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (40 trials), Australia (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 13, Phase 1: 3, Phase 1/2: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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