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Clinical trials and research at University Hospital, Essen

• 22Clinical trials
• 1New in 30 days
• 3Countries

Newest trials

All recruiting trials (22)

• High-precision radiosurgery followed by minimally invasive eye-sparing surgery for prominent uveal melanoma

  This study tests a modern, precise radiosurgery approach followed by a minimally invasive surgery to see if it can control the tumor while preserving vision in patients with high-prominence uveal melanoma.

  Recruiting at 3 sites University Hospital, Essen · Essen, Germany / NRW and 2 other locations · NCT07913412

• Body donation in HHT

  This study tests whether donated human tissue with and without vascular malformations from people with hereditary hemorrhagic telangiectasia can be analyzed to better understand the disease.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07826845

• Proton vs. Photon Radiation for Certain Grade 2–3 Gliomas

  This study tests whether proton therapy can better preserve thinking and memory than photon therapy for adults with IDH-mutated grade 2–3 gliomas who need radiation.

  Recruiting at 2 sites University Hospital, Essen · Essen and 1 other locations · NCT07750457

• Setmelanotide in BBS and related genetic obesity: real-world effects

  This study tests how well Setmelanotide works and is tolerated in people with Bardet-Biedl syndrome or similar genetic obesity conditions in routine clinical care.

  Recruiting Phase 4 University Hospital, Essen · Essen · NCT07674290

• Theranostic PET for target validation and tumor detection in solid cancers

  This is an observational effort to see how theranostic PET scans reflect tumor targets and help with staging, restaging, and treatment planning for adults with solid cancers.

  Recruiting University Hospital, Essen · Essen · NCT07664410

• Mental health and suicidal thoughts in adults with glioblastoma in Germany

  This project uses questionnaires and medical records to see if depression, anxiety, or other factors are linked to suicidal thoughts or behavior in adults with IDH wild-type glioblastoma.

  Recruiting at 5 sites University Hospital, Essen · Berlin and 5 other locations · NCT07409584

• Multimodal analysis of heart biopsy samples

  This project will take one extra small heart biopsy during a clinically needed procedure to test whether detailed molecular and immune analyses can find disease-specific signatures in adults with cardiomyopathies, myocarditis, cardiac amyloidosis, or after heart transplant.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07359690

• Quality of life and stress after pacemaker, ICD, CRT, or event recorder implantation

  This project will use medical exams and questionnaires to see if stress affects recovery and quality of life in people who have a pacemaker, ICD, CRT device, or event recorder implanted.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07343466

• Amyloid deposits in the heart and heart function in people with Alzheimer's disease

  This project will see if the same amyloid buildup found in Alzheimer's also shows up in the heart by adding a heart amyloid PET/MRI, an echocardiogram, and a dementia exam for people already having a brain amyloid PET.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07154394

• Hybrid 18F-Florbetaben PET/MRI to image cardiac amyloidosis

  This trial will test whether a combined 18F-Florbetaben PET and MRI scan can find imaging signs that predict major heart events in people with cardiac amyloidosis.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT07154381

• Breaking up arterial calcification with intravascular lithotripsy to improve blood flow in people with PAD

  This trial tests whether intravascular lithotripsy plus a drug-coated balloon works better than standard balloon angioplasty plus a drug-coated balloon for people with PAD and heavy artery calcification.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia and 1 other locations · NCT07130526

• Investigating the link between smell and survival in glioblastoma patients

  This study is trying to see if the ability to smell can give us clues about how well glioblastoma patients are doing and how long they might live.

  Recruiting at 2 sites University Hospital, Essen · Essen and 1 other locations · NCT06954636

• Registry for patients with systemic amyloidosis

  This study is collecting information from patients with systemic amyloidosis to better understand the disease and how different treatments work over time.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT06887283

• Evaluating the impact of stress on heart events in patients with peripheral artery disease

  This study looks at how different ways of measuring stress affect heart problems in people with peripheral artery disease.

  Recruiting University Hospital, Essen · Essen · NCT06887101

• Preoperative treatment for lung cancer with amivantamab and chemotherapy

  This study is testing if giving a new antibody treatment called amivantamab before surgery can help patients with certain types of lung cancer feel better and improve their outcomes.

  Recruiting at 4 sites Phase 2 University Hospital, Essen · Hasselt and 3 other locations · NCT06784791

• Registry assessing PSMA PET outcomes in prostate cancer

  This study is testing if PSMA PET imaging can help doctors better understand the outcomes for men with prostate cancer compared to traditional methods.

  Recruiting University Hospital, Essen · Essen · NCT06320223

• Improving radiation protection using genomic analysis

  This study is testing if analyzing DNA changes in blood samples can help us understand how some people are better at handling radiation exposure than others.

  Recruiting University Hospital, Essen · Essen, Germany / NRW · NCT06253338

• Using a smartphone app to improve statin therapy adherence in patients with atherosclerosis

  This study is testing if using a smartphone app to remind people with atherosclerosis to take their statin medication can help them stick to their treatment better than just regular care alone.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT05777655

• Using FAPI-PET imaging to detect tumors

  This study is testing if a new type of imaging called FAPI-PET can help doctors find tumors better in patients who are being checked for cancer.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT04571086

• Modular treatment approach for endometrial cancer with lymphadenectomy

  This study is testing a new surgical method for patients with intermediate to high-risk endometrial cancer to see if it can lower the chances of cancer coming back and improve survival without needing extra radiation treatment.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT04504006

• Examining the role of hypoxia in hereditary hemorrhagic telangiectasia

  This study looks at how low oxygen levels might affect people with hereditary hemorrhagic telangiectasia (HHT) and how it could change the way the disease develops.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT04469517

• Registry of patients undergoing coronary angiography

  This study looks at patients having coronary angiography to see what factors might affect their recovery and long-term health after the procedure.

  Recruiting University Hospital, Essen · Essen, North Rhine-Westphalia · NCT04196712

Quick answers

How many clinical trials run by University Hospital, Essen are recruiting right now?

22, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in Germany (22 trials), Belgium (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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