Mental health and suicidal thoughts in adults with glioblastoma in Germany

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls adults with IDH wild-type glioblastoma and collects standardized questionnaire data alongside a medical history, physical exam, and chart review. Participants complete validated instruments including the PHQ-8, GAD-7, a suicidality scale, EORTC-QLQ-C30, EORTC-QLQ-BN20, and a social support questionnaire. Clinical and imaging data from the medical record are combined with questionnaire responses to look for predictors or influencing factors for suicidal behavior. If unmet psycho-oncological needs are identified, participants are referred to appropriate services.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Newly diagnosed glioblastoma, IDH wild-type (CNS WHO classification of 2021) after finishing radiotherapy (before first recurrence)
* Age ≥ 18 years

Exclusion Criteria:

* Participants with clinically significant aphasia or language barrier as assessed by the investigator
* History of other malignant tumors
* Known tumor predisposition syndrome (e.g., Li-Fraumeni syndrome, Cowden syndrome, etc.)
* Recurrent glioblastoma

Where it's running

• Charite
  Berlin, Germany Recruiting
• University Hospital Essen
  Essen, Germany Recruiting
• University hospital Hamburg Eppendorf
  Hamburg, Germany Recruiting
• University hospital Heidelberg
  Heidelberg, Germany Recruiting
• University hospital Muenster
  Münster, Germany Recruiting
• University Hospital Knappschaftskrankenhaus Bochum
  Bochum, Germany Not yet recruiting

Study contacts

• Principal investigator: Sied Kebir, PD Dr. med. — University Hospital, Essen
• Study coordinator: Christoph Oster, Dr. med.
• Email: christoph.oster@uk-essen.de
• Phone: +49201-723-82598

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.