Registry assessing PSMA PET outcomes in prostate cancer
Official title: PROMISE Registry on Standardized Evaluation of PSMA-PET and Outcome in Prostate Cancer
Run by University Hospital, Essen · NCT06320223 · Data updated 2026-11-12
This study is testing if PSMA PET imaging can help doctors better understand the outcomes for men with prostate cancer compared to traditional methods.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 10000 (estimated) |
| Sponsor | University Hospital, Essen Academic / other |
| Locations | 1 site (Essen) |
| Status | Recruiting |
| Started | March 5, 2024 |
| Main results expected | March 5, 2034 |
| Study ends | March 5, 2035 |
| Registry record updated | March 20, 2024 |
| Trial ID | NCT06320223 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients with biopsy-proven prostate cancer who have undergone PSMA PET imaging for staging or re-staging.
✕Probably not a fit
Patients with neuroendocrine prostate cancer or those with metastasized malignancies other than prostate cancer may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the prognostic value of Prostate-Specific Membrane Antigen (PSMA) PET imaging in patients with prostate cancer. It will compare the outcomes of PSMA PET with established clinical prognostic scores across various stages of the disease. The study will include adult patients who have undergone PSMA PET for staging or re-staging and have at least three years of follow-up data available. The findings could enhance risk assessment and management strategies for prostate cancer patients.
Why it matters
Potential benefit: If successful, this study could improve prognostic accuracy and treatment guidance for patients with prostate cancer.
How similar studies have gone: Other studies have shown promising results with PSMA PET imaging in prostate cancer, indicating that this approach is gaining traction in the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion: * Adult patients with * biopsy/histo proven prostate cancer who * underwent PSMA PET (any type) * for staging or re-staging at any stage and who * have at least 3-year overall survival follow-up data available will be included consecutively. Exclusion: * Patients with neuroendocrine prostate cancer * Patients with metastasized or disseminated malignancy other than prostate cancer.
Where it's running
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University Hospital Essen
Essen, Germany Recruiting
Study contacts
- Principal investigator: Wolfgang P Fendler, M.D. — University Hospital, Essen
- Study coordinator: Wolfgang P Fendler, M.D.
- Email: redcap@ikim.nrw
- Phone: +492017232032
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This study will test whether 68Ga-XACP3 PET/CT can find tumor lesions in adults with prostate cancer or suspected recurrence compared with the standard 68Ga-PSMA PET/CT.
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This phase 1b trial tests a radiolabeled drug (AKY-2519) to see if it's safe and tolerable in adults with B7-H3 positive advanced solid tumors, including NSCLC and SCLC, with imaging to help guide use.
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PSMA-guided surgery and tissue-resident T cells in node-positive prostate cancer
This study tests whether PSMA-guided surgery can help identify and study tissue-resident T cells in prostate cancer that has spread to lymph nodes.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.