Evaluating the impact of stress on heart events in patients with peripheral artery disease
Impact of Stress on Cardiovascular Events in Patients with Peripheral Arterial Disease
This study looks at how different ways of measuring stress affect heart problems in people with peripheral artery disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Essen Academic / other |
| Locations | 1 site (Essen) |
| Trial ID | NCT06887101 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess how different methods of measuring stress relate to cardiovascular events in patients diagnosed with peripheral arterial disease (PAD). Given that PAD is associated with a high risk of severe cardiovascular complications, the study will explore the connection between acute and chronic stress and the occurrence of these events. By analyzing various stress measurement techniques, the research seeks to provide insights into the role of stress as a cardiovascular risk factor. The findings could help refine guidelines for managing cardiovascular health in PAD patients.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with lower extremity peripheral arterial disease.
Not a fit: Patients with conditions such as atrial fibrillation or those on specific antiarrhythmic medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for managing cardiovascular risks in patients with peripheral arterial disease by addressing stress as a significant factor.
How similar studies have performed: While the relationship between stress and cardiovascular diseases has been explored, this specific approach to measuring stress in PAD patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Diagnosis of lower extremity PAD based on: * Limb bypass surgery or * aorta-femoral bypass surgery or * percutaneous transluminal angioplasty revascularization of the iliac or infrainguinal arteries or * limb or foot amputation for arterial vascular disease or * intermittent claudication and one or more of either an ankle brachial index (ABI) of less than 0.90 or a peripheral artery stenosis (≥50%) documented by angiography or duplex ultrasound or carotid revascularization or asymptomatic carotid artery stenosis of at least 50% diagnosed by duplex ultrasound or angiography Exclusion Criteria: * atrial fibrillation * high premature ventricular contractions burden * pacemaker with constant ventricular pacing * antiarrhythmic drugs class I or III
Where this trial is running
Essen
- Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen — Essen, Germany (Recruiting)
Study contacts
- Study coordinator: Julia Lortz, MD
- Email: julia.lortz@uk-essen.de
- Phone: +49201723-84995
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.