Evaluating the impact of stress on heart events in patients with peripheral artery disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess how different methods of measuring stress relate to cardiovascular events in patients diagnosed with peripheral arterial disease (PAD). Given that PAD is associated with a high risk of severe cardiovascular complications, the study will explore the connection between acute and chronic stress and the occurrence of these events. By analyzing various stress measurement techniques, the research seeks to provide insights into the role of stress as a cardiovascular risk factor. The findings could help refine guidelines for managing cardiovascular health in PAD patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Diagnosis of lower extremity PAD based on:

* Limb bypass surgery or
* aorta-femoral bypass surgery or
* percutaneous transluminal angioplasty revascularization of the iliac or infrainguinal arteries or
* limb or foot amputation for arterial vascular disease or
* intermittent claudication and one or more of either an ankle brachial index (ABI) of less than 0.90 or a peripheral artery stenosis (≥50%) documented by angiography or duplex ultrasound or carotid revascularization or asymptomatic carotid artery stenosis of at least 50% diagnosed by duplex ultrasound or angiography

Exclusion Criteria:

* atrial fibrillation
* high premature ventricular contractions burden
* pacemaker with constant ventricular pacing
* antiarrhythmic drugs class I or III

Where it's running

• Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen
  Essen, Germany Recruiting

Study contacts

• Study coordinator: Julia Lortz, MD
• Email: julia.lortz@uk-essen.de
• Phone: +49201723-84995

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.