Sponsor or institution
Clinical trials and research at Univ of Maryland, College Park
As of November 12, 2026, Find a Trial lists 296 NIH-funded research projects at this institution, with $140.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 296NIH research projects
NIH-funded research (newest 40 of 296)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Understanding how fetal immobility changes tendon properties to prevent limb deformities
Researchers are studying why tendons in babies born with limited or no movement develop abnormally, aiming to improve treatments for limb deformities like arthrogryposis and clubfoot.
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Stepped Care, Peer-Delivered Help for ART Adherence and Substance Use in Primary Care
A peer-delivered, stepped-care program in busy primary care clinics helps people living with HIV stay adherent to ART and address substance use, aiming to fit resources and improve outcomes.
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Role of tryptophan breakdown and AHR in Leishmania resistance to antimony
This project looks at why a parasite that causes skin ulcers in South America may resist a common drug, by studying how human immune cells react to infection.
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How home noise affects children's development
A study looking at how everyday sounds at home influence how young children learn language and pay attention.
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Healthy Brain and Child Development study network
A nationwide effort to map how genes, environment, and experiences shape brain growth in thousands of babies and young kids from birth through age 10.
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Time-varying brain connections to better understand concussion impacts
A researcher will develop and test new computational methods to map how brain regions talk to each other over time, with a focus on concussion-related changes, to better guide future treatments.
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Topical ethanol gel for precise treatment of low-grade cervical dysplasia
A new topical gel using ethanol is being tested to treat low-grade cervical dysplasia in women, especially where access to regular care is limited.
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Impact of hospital-based health IT on care quality and equity for ADRD patients
A project examines how hospital health information technology affects the quality and equity of care for people with Alzheimer's disease and related dementias.
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Optimizing MOUD Access in Maryland with Data-Driven Plans
A Maryland-focused project aims to make more people with opioid use disorder start and stay on medications by using data to guide where mobile clinics, telehealth, and provider training should go.
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Culturally tailored Youth Mental Health First Aid for Asian American Parents
A program helps Asian American parents learn how to recognize and respond to their teens’ mental health signs in a culturally respectful way.
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Multimodal KeyScope Laparoscope to broaden access to keyhole surgery
A new laparoscope-based system is being developed to help more patients get minimally invasive surgery, including in rural and combat-zone settings.
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Glycoengineering antibodies to improve immune therapies
Aims to make antibody-based therapies more effective and consistent by precisely altering sugar structures and linking drugs to antibodies.
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Resistance Exercise Training for Blood Pressure and Blood Vessel Health in Middle-Aged Women
A large study will test whether 16 weeks of supervised resistance exercise can lower blood pressure and improve blood vessel health in women aged 40–64 with high blood pressure.
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Early-life factors shaping dementia risk and how biosocial pathways influence it
This NIH grant supports a network to study how life-long social, biological, and early-life factors contribute to dementia, with a focus on preventing dementia through understanding early origins.
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Trans-tympanic Endolysin: a noninvasive treatment for ear infections
A new, noninvasive approach uses specially delivered enzymes to fight middle ear infections through the eardrum, potentially reducing the need for systemic antibiotics in children.
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Pedagogical questions as a scaffold for kids' long-term thinking and learning
A study explores how parents’ guided questions during play can help children develop executive function skills over several years.
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Tryptophan breakdown and AHR pathways in leishmaniasis resistance to antimonial drugs
This project looks at why a parasite that causes cutaneous leishmaniasis in Colombia often resists a standard drug, by studying how the human immune system reacts at the cellular level.
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Phone text program to help people with HIV in Uganda and Zambia stop smoking
This program uses tailored text messages and nicotine patches to help people living with HIV in Uganda and Zambia quit tobacco.
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Daily stigma, racism, and alcohol use in LGBTQ+ adolescents of color
This project follows LGBTQ+ teens of color to see how daily experiences of stigma, discrimination, and structural racism relate to alcohol and other substance use.
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Acute and Chronic Social Stress and Health Trajectories in Filipino, Korean, and Indian American Young Adults
This NIH grant follows 18–19 year old Filipino, Korean, and Indian Americans to see how daily stress affects their use of alcohol and drugs, mood, and health over three years.
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Mechanisms of plant membrane stabilization and repair
Scientists are studying how plant cells protect and fix their membranes on their own, which could explain how plants resist fungal attack.
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Racial stigma and substance-use risk among African American young adults
This grant explores how racial stigma may trigger brain and stress responses that increase the risk of using substances among African American young adults.
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Glycan clues to a stronger mucus barrier against respiratory viruses
A study from the University of Maryland aims to understand how the mucus lining in the lungs blocks or allows respiratory viruses to pass through, with the goal of making this barrier more effective for people with airway diseases.
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Understanding how TB bacteria tamps down the body's alarm system
This NIH grant studies how Mycobacterium tuberculosis blocks a key immune signal to help the bacteria cause tuberculosis, with the goal of finding new ways to boost the body's defenses.
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Cellular sensing of mechanics in breast cancer biology
Researchers are studying how breast cancer cells and immune cells feel and respond to the stiffness of their surroundings, aiming to connect mechanical signals to changes in gene activity.
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Social stress, epigenetics, and immune aging in bats
This grant studies how social stress and aging affect the immune system in bats, a unique species with long lives and strong social bonds.
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Stability and Change in Psychosocial Risk and Protective Profiles for Substance Use in Adolescents With and Without ADHD
A study looking at how friendships, family, and school factors relate to teen substance use in kids with and without ADHD, using a patient-centered approach.
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How the orbitofrontal brain area helps us learn signals and choices
This project studies how the brain’s orbitofrontal area helps animals learn what cues mean and guide their choices.
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How prior knowledge helps memory in aging and Alzheimer's disease
This grant studies how what we already know shapes what we remember, especially in older adults and people with Alzheimer's disease.
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Peer-delivered behavioral activation to help people with OUD in rural areas using a mobile telemedicine unit
A rural, mobile telemedicine program uses a peer-delivered behavioral activation approach to help people with opioid use disorder who also use other substances stay in treatment and reduce opioid use.
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Understanding how biomolecules shape locally delivered nanomedicines
A researcher at the University of Maryland is studying how proteins and other biomolecules on small drug-carrying particles affect how the medicine behaves when released directly at a site in the body.
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Image-guided ethanol ablation for treating cervical dysplasia
A doctor-led study is exploring a low-cost, image-guided treatment using ethanol to target cervical dysplasia in women, aiming to make care more accessible in underserved communities.
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Development Core supports population research collaboration and training
A core at a major university funds and promotes high-quality population research and collaboration, with a focus on diversity, mentorship, and community engagement.
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Administrative Core for Population Research Center (MPRC)
A core administrative grant supports a population research center to run smoothly and effectively, enabling researchers to work across campus and with the community.
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Maryland Population Research Center: infrastructure to advance population health and inequality research
A multi-year NIH grant supports a collaborative research center at the University of Maryland that strengthens population science and data methods to better understand health, gender, family, migration, and social inequities.
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Joint Institute for Food Safety and Applied Nutrition: partnering to protect the public from foodborne risks
This grant supports a joint program to strengthen food safety and nutrition through collaborative research and education that helps prevent food-related health problems.
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Peer-delivered stepped care to help people with HIV stick to ART and reduce substance use
A peer-delivered stepped care program aims to help people living with HIV who use substances stay on their HIV medicines and get extra substance-use support in primary care.
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Prevention of Attachment Insecurity and Related Child Problems in Early Head Start
A structured program tests whether teaching caregivers in high-risk families to respond sensitively can improve attachment, regulate physiology, and reduce behavior problems in young children.
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Biomaterial Models of Ancestral Contributions to Wound Healing
Researchers are studying how ancestry may influence skin wound healing using lab models to uncover clues for more personalized therapies.
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AI-guided molecular simulations to design better medicines
This project uses AI-enhanced computer simulations to design drugs that account for changing protein shapes, aiming to help people who need more precise targeted medicines like some cancer patients.
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