NIH-funded research NIH-funded research

Mechanisms of plant membrane stabilization and repair

Official title: Mechanisms of cell-autonomous plasma membrane stabilization and repair in plants

Funded at Univ of Maryland, College Park · NIH-11401053 · Data updated 2026-11-12

Scientists are studying how plant cells protect and fix their membranes on their own, which could explain how plants resist fungal attack.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park
NIH-funded
Lab location1 site (College Park, United States)
Project startSeptember 1, 2025
Project endAugust 31, 2030
Funding year2026
Award (this year)$384,269
NIH project number5R35GM158354-02
Project IDNIH-11401053 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are plants or plant tissues (e.g., Arabidopsis leaves) used in laboratory experiments researching membrane repair mechanisms.

Less likely to help

There are no direct patient benefits since this is plant research, not human medical research.

What this research studies

This project will explore how plant cell membranes stay intact and repair themselves without help from neighboring cells. Researchers will use Arabidopsis and CRISPR techniques to disrupt specific genes and observe effects on membrane stability. The work aims to uncover molecular players involved in CAPMR in plants and how these processes relate to disease resistance. Findings could lead to new approaches for protecting crops from fungal pathogens.

Why it matters

Potential benefit: Understanding CAPMR in plants could lead to crops with stronger disease resistance and better tolerance to environmental stresses.

How similar studies have gone: Prior work in animals suggests membrane repair pathways exist; this project explores plant-specific CAPMR, which is a novel area with potential for impactful discoveries.

Where this research is happening

  • Univ of Maryland, College Park
    College Park, United States
    Active

Researchers

  • Principal investigator: Xiao, Shunyuan — Univ of Maryland, College Park
  • Study coordinator: Xiao, Shunyuan

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.