Topical ethanol gel for precise treatment of low-grade cervical dysplasia
Official title: Topical ethanol gel to precisely treat low-grade cervical dysplasia
Funded at Univ of Maryland, College Park · NIH-11463813 · Data updated 2026-11-12
A new topical gel using ethanol is being tested to treat low-grade cervical dysplasia in women, especially where access to regular care is limited.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Maryland, College Park NIH-funded |
| Lab location | 1 site (College Park, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $698,466 |
| NIH project number | 1R01CA308363-01A1 |
| Project ID | NIH-11463813 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with persistent low-grade cervical dysplasia who have limited access to routine follow-up and treatment in safety-net settings.
✕Less likely to help
Patients with high-grade dysplasia or cervical cancer requiring more extensive intervention may not benefit from this topical approach.
What this research studies
This project aims to offer a more accessible treatment option for low-grade cervical dysplasia using a targeted ethanol gel applied to the cervix. It focuses on safety, dosing, and how well the gel can ablate diseased tissue while preserving healthy tissue. The approach could reduce the need for full cervical procedures and improve care continuity for women who may have difficulty returning for repeated follow-up. The study likely involves clinical evaluation in real patient settings, potentially including follow-up visits to monitor response and any side effects.
Why it matters
Potential benefit: If successful, the gel could provide a simpler, cervix-sparing treatment that works even where healthcare access is limited.
How similar studies have gone: Prior ablation methods exist but often remove more tissue and require resources; this approach is being tested for precision and feasibility in real-world settings.
Where this research is happening
-
Univ of Maryland, College Park
College Park, United States Active
Researchers
- Principal investigator: Maisel, Katharina — Univ of Maryland, College Park
- Study coordinator: Maisel, Katharina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.