Sponsor or institution
Clinical trials and research at St. John's University
As of November 12, 2026, Find a Trial lists 36 NIH-funded research projects at this institution, with $8.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 36NIH research projects
NIH-funded research (36)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Molecular clues to how proton channels in cells open, close, and move protons in cancer and surrounding tissues
A scientist at ST. JOHN'S UNIVERSITY is studying how proton channels (Otop family) work at the molecular level and how their behavior affects cancer and related conditions.
-
Biocontained whole-cell biosensors to detect dysbiosis and inflammation
A scientist team is creating safe, engineered bacteria that can sit in saliva and signal early signs of imbalance in the microbiome and inflammation, potentially helping with early diagnosis.
-
New highly selective PARP1 inhibitors for brain cancers and beyond
A new class of PARP1 inhibitors is being developed to treat cancers with BRCA defects by targeting PARP1 more selectively and avoiding brain toxicity and drug resistance.
-
Iron and ferroptosis: how iron metabolism shapes a cell’s self-destruction in cancer
A researcher at ST. John’s University is testing how iron in cancer cells affects ferroptosis, a unique form of cell death, to find new ways to influence tumor behavior.
-
MG53 and GsdmD interaction to protect heart cells after a heart attack
A study to see if MG53 can team up with GsdmD to reduce inflammatory cell death and limit heart damage after a heart attack.
-
16α-hydroxylated bile acids and how they control energy intake and liver fat
A study to understand how a specific form of bile acid (with a 16α hydroxyl group) influences how much people eat and how fat is processed in the liver, using cells and animal models.
-
Understanding how language shapes our brain’s processing of sounds
This grant studies how experience with different languages changes how the brain processes spoken sounds, which could help explain why people hear and understand speech differently.
-
Triple quadrupole LC-MS/MS instrument to boost pharmaceutical research
A high-sensitivity mass spectrometry instrument will be acquired to support drug research and teaching at St. John’s University, enabling precise measurements of drug molecules and biomarkers.
-
Repurposing FDA-approved Drugs for Lung Diseases with AI
A strategy uses an AI tool to find existing drugs that could help people with PAH or IPF.
-
Combination therapy targeting tumor and surrounding stroma in pancreatic cancer
Aims to improve treatment for pancreatic cancer by delivering a targeted therapy together with a agent that changes the tumor environment to help drugs work better.
-
Role of Lipocalin Prostaglandin D2 Synthase (L-PGDS) and PGD2 in NAFLD
A research project explores whether a specific liver enzyme and its product influence the development of non-alcoholic fatty liver disease (NAFLD).
-
PD-L1's control of cancer cell survival genes
Researchers are looking at whether the protein PD-L1 helps ovarian and prostate cancer cells keep survival genes active, which could affect how these cancers respond to treatment.
-
Understanding how p53 affects immune responses and cancer progression
This study is looking at how a protein called p53 helps control another protein linked to inflammation and cancer, with the hope of finding new ways to fight these conditions and improve treatments for people dealing with them.
-
Understanding a protein's role in non-alcoholic fatty liver disease
This project explores how a specific protein and its byproduct might contribute to non-alcoholic fatty liver disease, hoping to find new ways to help people with this condition.
-
How children's brains process music and speech tones across cultures
This project looks at how music lessons and tonal languages shape brain responses in children ages 5–10.
-
Nose-delivered glowing marker to guide brain tumor surgery
This project is testing a nose-delivered fluorescent agent that lights up brain tumors so surgeons can see and remove them more accurately in adults with brain cancer.
-
How our brains process sounds and learn different languages
This project explores how the brain processes speech sounds differently based on the language you grew up speaking.
-
How certain chemicals make skin layers separate and cause blisters
Researchers are exploring how nitrogen mustard and similar chemicals cause the top layer of skin to detach and form painful blisters so that better treatments can be developed for chemical skin injuries.
-
A new method to prevent preterm birth using a vaginal drug delivery system.
This study is testing a new way to deliver a treatment that could help prevent preterm birth by reducing inflammation, and it's designed for pregnant individuals who are at risk of having their babies too early.
-
Using an antiepileptic drug to treat aggressive brain tumors
This study is looking at whether an existing epilepsy medication called stiripentol can be used to help treat glioblastoma, a tough type of brain tumor, by seeing how it affects cancer cells and if it can get past barriers in the brain, with the hope of finding better treatment options for patients.
-
Combining targeted therapy with a stroma-modulating agent for pancreatic cancer
This study is exploring a new way to treat pancreatic cancer by using a special combination of drugs that not only attack the cancer cells but also help the surrounding tissue, making it easier for the medicine to work better, and patients may have the chance to participate in testing how safe and effective this treatm
-
How PD-L1 affects the stability of cancer-related mRNA
This study is looking at how a protein called PD-L1 affects the way certain genes help cancer cells survive in ovarian and prostate cancer, with the hope that understanding this could lead to better treatments for patients.
-
Investigating skin blistering caused by toxic substances
This study is looking at how certain harmful substances can cause skin blisters and aims to find ways to protect the skin from damage, which could help people who suffer from skin injuries due to chemicals.
-
Understanding how sperm cells become activated in a tiny worm.
This study looks at how sperm in tiny worms called C. elegans get ready to swim and fertilize eggs, aiming to understand the genes and signals that help this process, which could also shed light on fertility problems in other animals.
-
Understanding how a specific enzyme affects fatty liver disease
This study is looking at how a specific protein and its byproduct might affect the development of non-alcoholic fatty liver disease (NAFLD), especially in people who are dealing with insulin resistance and obesity, to help find better ways to treat the condition.
-
Using special nanoparticles to improve brain cancer surgery through the nose.
This study is looking at a new way to help brain cancer surgeons find tumors more easily during surgery by using special tiny carriers that deliver imaging agents through the nose, which could lead to safer and more effective surgeries for patients.
-
Understanding how language experience affects speech perception in the brain
This study looks at how hearing sounds from your native language affects how your brain understands speech, and it's for adults who speak Polish and English.
-
Understanding how music affects brain development in children
This study is looking at how learning music and speaking different languages can help kids aged 5 to 10 develop their brains, and it aims to find out how these skills work together to improve how they hear and understand sounds.
-
Investigating skin blistering caused by toxic substances
This study is looking at how certain harmful substances can cause skin blisters and aims to find out how the immune system and skin proteins are involved, with hopes of discovering better ways to treat skin injuries for people affected by these toxins.
-
Understanding how RNA splicing affects a calcium channel linked to neurological disorders.
This study is looking at how a process called RNA splicing affects a calcium channel that helps nerve cells work properly, with the hope of finding new ways to help people with conditions like spinocerebellar ataxia, epilepsy, and autism.
-
Understanding how p53 affects immune responses and cancer development
This study is looking at how a protein called p53 helps control another protein linked to inflammation and cancer, with the hope of finding new ways to fight these diseases and improve treatments for people affected by them.
-
Creating a new inhalable COVID-19 vaccine that doesn't need refrigeration
This study is testing a new inhalable COVID-19 vaccine that doesn't need to be kept cold, making it easier to give to people, especially in hard-to-reach places or during emergencies.
-
Understanding how certain proteins help control gene activity and maintain DNA stability
This study is looking at how certain proteins help control the end of gene reading in our cells, especially when there's DNA damage or stress, to keep our genes stable and healthy, which could help us understand more about cancer and improve treatments for patients.
-
Combining targeted therapies to treat difficult lung cancer cases
This study is testing a new way to treat advanced non-small cell lung cancer by using a special self-injectable medicine that targets specific proteins causing the cancer, with the hope of making treatments work better for patients.
-
How changes in RNA splicing affect a calcium channel linked to neurological disorders.
This study is looking at how a process called RNA splicing affects a calcium channel that's important for nerve cell activity, which could help us understand how problems with this process might be linked to conditions like spinocerebellar ataxia, epilepsy, and autism.
-
Understanding and targeting the mechanisms that help neuroblastoma tumor cells survive and grow
This study is looking at how some tough neuroblastoma cancer cells manage to survive treatment, with the goal of creating new therapies that can better target and eliminate these stubborn cells to help prevent the cancer from coming back.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.