Sponsor or institution
Clinical trials and research at Old Dominion University
As of November 12, 2026, Find a Trial lists 3 clinical trials run by Old Dominion University that are recruiting, in United States. There are also 61 NIH-funded research projects at this institution, with $26.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 61NIH research projects
- 1Country
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Olive oil supplementation during cardiac rehab for heart failure with reduced ejection fraction | — | Norfolk, Virginia | Recruiting | Jun 12, 2026 |
| Mobile app to boost cardiovascular health and exercise motivation during pregnancy | — | Norfolk, Virginia | Recruiting | Sep 10, 2025 |
| Examining the effects of stopping exercise on blood sugar and blood vessel health in older adults | — | Norfolk, Virginia | Recruiting | Jul 21, 2022 |
All recruiting trials (3)
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Olive oil supplementation during cardiac rehab for heart failure with reduced ejection fraction
This study tests whether adding extra-virgin olive oil during a cardiac rehabilitation program is doable and helpful for people with HFrEF.
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Mobile app to boost cardiovascular health and exercise motivation during pregnancy
This trial will test whether using the BumptUp mobile exercise app for eight weeks helps healthy pregnant women in their second trimester increase motivation to exercise and improve cardiovascular measures.
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Examining the effects of stopping exercise on blood sugar and blood vessel health in older adults
This study is testing how taking a break from exercise affects blood sugar and blood vessel health in older adults who usually stay active, and whether getting back to exercise can help fix any problems that arise.
NIH-funded research (newest 40 of 61)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Immunomodulatory therapy to speed up healing after oral cavity injuries in kids
A new approach using a drug called FTY720 aims to improve healing and reduce pain after oral injuries or palate surgery in children.
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Deciphering how Listeria breaches the brain’s barrier to cause neurolisteriosis
Scientists are studying how the bacteria Listeria monocytogenes crosses the brain barrier to cause severe brain infections, with potential to guide new treatments.
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Microenvironmental Rescue of Age-Related Cellular Dysfunction in a 3D Bioprinted Mammary Model System
A research project aims to test new ways to restore aging mammary tissue function using a 3D bioprinted model and cell interactions that may reduce disease-related decline.
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Core biomarker lab for breast cancer BRCA2 and aggressive prostate cancer
A patient-facing biomarker program at a university lab aims to find and validate tests that help identify aggressive prostate cancers and BRCA2-related risks earlier.
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Biomarker Lab for better prostate cancer risk and progression tests
Researchers are building and validating protein and gene-based tests from urine and tissue to better identify aggressive prostate cancer early so men can get the right treatment.
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Biomarkers to identify aggressive prostate cancer early
A patient-friendly program to find and validate biomarkers in urine and tumor tissue that can flag aggressive prostate cancer early so men can get the right treatment sooner.
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Biomarker Center for Prostate Cancer Risk and Progression
A program to find and validate molecular markers in urine and prostate tissue that can tell which localized prostate cancers are likely to become aggressive.
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Chronic Ankle Instability and Aging: Effects on Movement, Joint Health, and Daily Life
A potential study asks how aging and chronic ankle instability together affect how people move, balance, and stay active.
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Transdermal HIV prevention for breastfeeding infants using bnAbs on a patch
A child-focused HIV prevention approach uses a patch to deliver protective antibodies through the skin to babies who are breastfed.
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Multi-Resolution Docking Tools for Cryo-EM Structures
A research project to improve computational methods for fitting atomic models into cryo-EM and cryo-ET maps, helping scientists understand complex cellular machinery.
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Computational imaging and molecular data modeling to track brain tumor recurrence
A computer-based approach uses AI and data from brain scans and molecular tests to help detect when glioblastoma may come back or change after treatment, with the goal of guiding better care.
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Cardiac muscle protein C interactions with thin filaments in heart disease
A project at Old Dominion University is looking at how a heart protein called cMyBP-C helps the heart beat properly and how mutations linked to heart disease change its function.
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HIV, cocaine, and brain fat: how tiny brain cells react and what this means for NeuroHIV
This grant looks at how HIV and cocaine change brain cell metabolism and fat handling, which may contribute to NeuroHIV symptoms.
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Understanding how fat, foam cells, and inflammation drive benign prostate problems
A long-term study will look at how lipid buildup and foam cells in the prostate contribute to common, bothersome urinary symptoms in aging men.
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In situ microneedle depots for targeted drug delivery
A new, tiny needle-like patch idea is being tested to deliver medicines directly where they’re needed, potentially reducing side effects for liver and kidney conditions and hard-to-treat infections.
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Desmosterol’s role in B1a cells and atherosclerosis
A new study looks at how a cholesterol-related molecule called desmosterol affects a special type of immune cell (B1a cells) and its impact on hardening of the arteries.
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Membrane response to electrical stress to improve safe, precise therapies
This grant studies how cell membranes react to brief electrical pulses to better control therapies like cancer ablation and heart rhythm treatments.
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Protecting the gut after serious radiation with YK-4-250
A new drug called YK-4-250 aims to protect the intestines and improve survival after high‑dose radiation exposure.
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New cobalt methods to make bioactive natural products
A research grant at Old Dominion University is exploring simpler, modular ways to make biologically active natural compounds that could become new medicines or agrichemicals.
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Targeting age-related cell changes in cystic fibrosis lungs
Researchers will test whether changing epigenetic signals can reduce harmful aging-like changes in lung cells of people with cystic fibrosis.
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How blood-flow forces affect cancer cells that travel in the bloodstream
This work looks at whether the forces of blood flow help cancer cells survive and later spread in people with cancer.
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Synthetic tooth‑in‑eye corneal implant
A lab‑made corneal implant meant to replace the tooth-and-bone piece of 'tooth‑in‑eye' surgery for people with severely damaged corneas.
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Urine and tissue biomarker lab to improve prostate cancer risk prediction
This project will develop urine- and tissue-based tests and decision tools to help find men with prostate cancer who are likely to have aggressive disease, including those with BRCA2 gene changes.
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Better tests to spot aggressive prostate cancer
This project develops urine and tissue tests to help find which men with early prostate cancer are likely to have aggressive disease.
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Better tests to find aggressive early prostate cancer
This project develops urine and tissue biomarker tests and decision tools to help men with early prostate cancer learn whether their cancer is likely to be aggressive and needs treatment.
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Better urine and tissue tests to find aggressive prostate cancer
This project will develop urine- and tissue-based tests and decision tools to help men with early prostate cancer, including those with BRCA2 gene changes, know who has aggressive disease and who can safely wait.
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Tiny dissolving skin patch that delivers protective antibodies to breastfed babies
A painless microneedle patch that delivers HIV-blocking antibodies to help protect infants who are breastfed by mothers with HIV.
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Developing a long-lasting injectable system for HIV prevention and contraception
This study is working on a new gel that can be injected to provide two important medications—one to help prevent HIV and another for birth control—over a long time, and they want to make sure it’s safe and effective while also listening to what potential users think about it.
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Investigating RNA modifications in mouse eggs
This study is looking at how a process called RNA editing, especially involving an enzyme named ADAR1, affects the quality of eggs in mice, which could help us understand fertility and birth defects in both young and older mice.
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Developing RNA therapies to help mature eggs for fertility
This study is exploring a new way to help women who have trouble with their eggs maturing properly due to genetic issues, using a special treatment that involves injecting a type of RNA into the eggs to improve their chances of fertilization and pregnancy.
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Understanding Lipids and Immune Cells in Benign Prostate Enlargement
This research explores how fat buildup and certain immune cells contribute to prostate enlargement in aging men, hoping to find new ways to help.
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Understanding Brain Inflammation and Mental Health Challenges in People with HIV
This project explores how brain inflammation contributes to depression and anxiety in people living with HIV, especially when antiretroviral medications and cocaine use are also present.
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Investigating how immune cells affect blood vessel health in high blood pressure.
This study is looking at how certain immune cells might affect blood vessel health in people with high blood pressure, and it hopes to find new ways to improve their condition by testing healthy immune cells in animal models.
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Blocking interleukin 12 may protect insulin-producing cells and blood vessels in type 2 diabetes.
This study is looking at how a substance called IL-12 affects people with type 2 diabetes, specifically how it might harm insulin-producing cells and blood vessels, and it hopes to find ways to block IL-12 to help protect these important parts of the body and reduce diabetes-related health issues.
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New non-invasive deep brain stimulation using temporal interference
This project is creating a way to stimulate deep brain areas from outside the head to one day help people with brain problems like stroke or movement and memory issues.
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Exploring how to improve compliance with smoke-free housing policies
This study is looking at how smoke-free housing rules can help keep people safe from secondhand smoke, especially focusing on what low-income smokers think about these rules and how fair they feel they are, so we can find better ways to make sure everyone follows them.
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Exploring glycosylated RNAs as new targets for aggressive prostate cancer.
This study is looking at special changes in RNA that might affect how prostate cancer grows and how well patients do, with the goal of finding better ways to treat advanced prostate cancer and help doctors make more personalized treatment plans for men facing this disease.
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Improving COVID-19 testing trust in communities
This study is all about helping low-income Black residents in Southeastern and Central Virginia feel more comfortable with public health services, especially after the challenges of the COVID-19 pandemic, by creating a friendly program that encourages testing and vaccination through community support and trusted peer m
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Investigating how to reduce aging effects in the lungs of cystic fibrosis patients
This study is looking at how aging affects the lungs of people with cystic fibrosis and is exploring new ways to help improve lung health and quality of life by targeting the aging process in lung cells.
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Imaging and molecular tools to detect returning brain tumors
This project uses brain scans and tumor molecular data with AI to help doctors spot when glioblastoma tumors come back in adults.
Quick answers
How many clinical trials run by Old Dominion University are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.