Examining the effects of stopping exercise on blood sugar and blood vessel health in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how temporarily stopping exercise affects glycemic control and endothelial function in older adults who are physically active. It aims to determine the speed at which these impairments occur after an acute period of inactivity and whether a return to exercise over three days can restore these functions. The focus is on understanding the relationship between physical activity and cardiovascular health in an aging population, which is less understood compared to younger individuals. Participants will undergo a controlled removal of exercise to assess these changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 55 years and older, 18-40 years old
2. Healthy, physically active, performing at least 90 min/week of physical activity
3. Free of physical limitations that may interfere with alterations in daily physical activity levels

Exclusion Criteria:

1. Physician diagnosed HIV, hepatitis, or tuberculosis.
2. Body weight change of greater than 5% within the previous 2 months
3. Smoking within the previous 2 months.
4. Taking medications that alter blood glucose levels

Where it's running

• Old Dominion University
  Norfolk, Virginia, United States Recruiting

Study contacts

• Study coordinator: Leryn Reynolds
• Email: lreynold@odu.edu
• Phone: 757-683-4974

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.