NIH-funded research NIH-funded research

Chronic Ankle Instability and Aging: Effects on Movement, Joint Health, and Daily Life

Official title: Chronic Ankle Instability and Aging: Combined Effects on Physical Function, Joint Health, and Daily Activity

Funded at Old Dominion University · NIH-11396537 · Data updated 2026-11-12

A potential study asks how aging and chronic ankle instability together affect how people move, balance, and stay active.

More Aging research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOld Dominion University
NIH-funded
Lab location1 site (Norfolk, United States)
Project startAugust 20, 2025
Project endJune 30, 2029
Funding year2026
Award (this year)$154,969
NIH project number5R16GM159643-02
Project IDNIH-11396537 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with chronic ankle instability who are 21 years or older and willing to participate in longitudinal follow-up.

Less likely to help

Individuals without CAI or those unwilling to commit to long-term follow-up may not benefit.

What this research studies

This project focuses on adults with chronic ankle instability to understand how aging influences balance, walking, reaction time, and ankle joint health over time. The researchers will follow participants over several years to see how activity levels and joint health change with age. They will look at physical function and daily activities to identify factors that might help people stay active and reduce joint problems. The study is designed to reveal how aging and CAI interact, which could guide future therapies and recommendations.

Why it matters

Potential benefit: If successful, findings could inform ways to preserve balance, mobility, and joint health in adults with CAI as they age.

How similar studies have gone: Previous research shows age-related declines in balance and joint health in CAI, but long-term interaction with aging remains to be clarified.

Where this research is happening

  • Old Dominion University
    Norfolk, United States
    Active

Researchers

  • Principal investigator: Mccann, Ryan — Old Dominion University
  • Study coordinator: Mccann, Ryan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.