Sponsor or institution
Clinical trials and research at Oklahoma State University Stillwater
As of November 12, 2026, Find a Trial lists 76 NIH-funded research projects at this institution, with $26.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 76NIH research projects
NIH-funded research (newest 40 of 76)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Iron and scar-forming cells in the lungs (IPF)
Researchers are exploring how iron in the lungs may drive the scarring seen in idiopathic pulmonary fibrosis and whether this could lead to new therapies.
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Understanding how a calcium sensor helps Pseudomonas infections resist the immune system
This project looks at how the bacteria Pseudomonas aeruginosa uses a calcium sensor to survive and cause infections in people with conditions like cystic fibrosis.
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ERK1/2 signaling and SARS-CoV-2 immune dysregulation in the lung
Aims to see if blocking ERK1/2 in immune cells can reduce dangerous lung inflammation from SARS-CoV-2 and boost antiviral defenses.
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OADDL Testing Support for Vet-LIRN (Veterinary Network)
A veterinary diagnostic lab in Oklahoma will support national animal health surveillance and testing programs by handling clinical samples, animal feeds, environmental samples, and necropsies to help keep animal health and food safety safer.
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How social life affects cognitive health in older adults in rural and urban areas
A study following older adults in rural and urban areas to see how social networks and daily activities relate to thinking skills over time.
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Biophysical view of how enzymes work to help fight cancer
A scientist is studying how enzymes work on a deep, molecular level to help design better cancer drugs with fewer side effects.
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Environmental microplastics, cadmium, and digestion: how they affect health and safety
This project looks at how tiny plastics and cadmium in our food and water interact in the body and what that could mean for our health.
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Stress-related signals triggering herpes relapses in nerve cells
This grant looks at how stress hormones can wake up herpes from latency in nerve cells and what this means for people who get recurrent eye or brain infections.
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Brainstem glial aging and dysfunction in obesity-related high blood pressure
This NIH grant explores how support cells in the brainstem (glia) become dysfunctional in obesity and contribute to high blood pressure, with findings that could lead to better treatments.
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How TB Bacteria Acquire Iron from Heme in Our Bodies
This NIH grant would study how the tuberculosis germ gets iron from heme and hemoglobin inside the human body, which is important for its growth and disease.
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Gut–brain link in teen and young adult opioid addiction
This project looks at whether changes in the gut microbiome and a common brain gene (BDNF Val66Met) influence how opioids affect adolescents and young adults.
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How mouth and throat bacteria produce natural antibiotic compounds
Researchers aim to find natural antibacterial compounds made by mouth and throat bacteria that could help protect people from infections.
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Tweaking gut viruses to target harmful gut bacteria
Researchers are changing tiny gut viruses so they can target and control bacteria that cause infections.
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Mouth bacteria that may speed up oral cancer
This work looks at whether specific mouth bacteria help oral squamous cell carcinoma grow and spread in people who have or are at risk for oral cancer.
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Targeting PFK-2 to help heart cells grow after injury
Aims to test whether dialing up a specific heart metabolism enzyme can encourage heart cells to multiply and repair damage after a heart attack.
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Understanding how certain viruses prevent infections from other viruses
This study is looking at tiny viruses that infect bacteria to see how they protect themselves from getting attacked by other viruses, which could help us understand more about how viruses behave in our gut.
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Iron buildup and lung scarring in idiopathic pulmonary fibrosis
This project looks at whether iron buildup inside lung cells causes or worsens scarring in people with idiopathic pulmonary fibrosis.
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Using routine lab tests and health records to spot diabetic eye disease earlier
This project uses patterns in routine blood tests and electronic health records to help identify adults with diabetes who may have early diabetic retinopathy so they can get timely eye care.
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Investigating how iron contributes to lung fibrosis
This study is looking into how tiny iron particles from things like asbestos and cigarette smoke might play a role in causing idiopathic pulmonary fibrosis (IPF), a tough lung disease, and aims to find new ways to help treat it by understanding how these particles affect lung cells.
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Rules of Genome Evolution and Design in Small, Single-Stranded DNA Phages
This project explores how tiny ssDNA phages evolve and how their genetics could be harnessed, with potential implications for gut health and microbiome balance.
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Understanding and treating severe lung damage from viruses like SARS-CoV-2
This research explores how certain viruses, like SARS-CoV-2, cause severe lung inflammation and damage, aiming to find new ways to protect patients.
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AI models to predict how dry powder inhalers deliver medicine in different lungs
This project builds AI-driven models to predict how dry powder inhalers deliver medicine across different inhalers, formulations, and people who use them.
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Understanding how brain changes in obesity lead to high blood pressure
This study is looking at how certain brain cells might play a role in high blood pressure caused by obesity, and it hopes to find new ways to help manage blood pressure for people dealing with this condition.
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Kids' mental health and exposure to tobacco, cannabis, and vaping smoke
This project looks at how exposure to cigarette smoke, vaping vapor, and cannabis smoke at different ages relates to children's mood and behavior over time.
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Hearing and sound‑localization problems in Fragile X syndrome
This work looks at whether reduced myelin (nerve insulation) causes trouble hearing and locating sounds in people with Fragile X syndrome.
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Investigating how myeloid cells respond to SARS-CoV-2 and affect lung immunity
This study is looking at how certain immune cells in the lungs react to the COVID-19 virus and cause inflammation, and it's aimed at finding ways to lessen this harmful response while still helping the body fight off the virus.
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Understanding how social life affects memory as we age in different communities
This project wants to learn how social connections and daily activities influence memory changes in older adults living in both rural and city areas.
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Unlocking the Secrets of Enzymes for Better Treatments
This project aims to deeply understand how enzymes work, which can help create new and improved medicines for various human diseases, including cancers.
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How bacteria sense stress and influence antibiotic resistance
Researchers are testing ways to block or hijack bacterial stress sensing so antibiotics can kill resistant infections more effectively.
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Improving the effectiveness of inhalers for patients using machine learning.
This study is looking to improve how well dry powder inhalers work by using smart technology to predict how well the medicine gets to your lungs, taking into account things like the inhaler's design and how you use it, so that everyone can get the best results from their inhalers, whether they are brand-name or generic
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Exploring how a beneficial nose bacteria can fight harmful Staphylococcus aureus
This study is looking at how a helpful bacterium in your nose can fight off a harmful one that causes infections, with the goal of finding new treatments for people who are more vulnerable to these infections.
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Understanding how proteins transfer protons and change structure
This study is looking at how proteins change when they work, focusing on a special part called histidine, to help us understand how proteins help our bodies signal, produce energy, and carry out important tasks.
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Creating personalized preventive care recommendations using electronic health records.
This study is working on a new system that gives personalized health advice based on your medical history and lifestyle, so you can get the best preventive care just for you, rather than a generic plan that might not fit your needs.
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Support for veterinary diagnostic testing and surveillance programs
This study is all about helping the Oklahoma Animal Disease Diagnostic Laboratory do a better job of testing samples from animals, their food, and the environment to keep our pets and livestock healthy.
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How HSV-1 affects inflammation and aging in female mice.
This study looks at how the HSV-1 virus affects inflammation and aging in female mice, especially how it can wake up from being inactive and impact their brains, with the goal of finding new ways to help people dealing with HSV-1 related issues.
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Exploring the link between the gut microbiome and opioid addiction in adolescents
This study is looking at how the bacteria in our gut might affect young people who are struggling with opioid addiction, especially those using oxycodone, and it will also explore whether a special treatment using healthy gut bacteria could help improve their gut health and brain function.
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Understanding how bacteria in the human aerodigestive tract produce antibiotics in response to pathogens
This study is looking at how friendly bacteria in our throat and digestive system can help fight off harmful germs by producing helpful substances, like antibiotics, which could lead to safer treatments for infections.
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Understanding and manipulating gut viruses to improve health
This study is exploring how tiny viruses in our gut can be used to help fight off bad bacteria, with the hope of finding new ways to improve gut health and prevent infections.
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Investigating how oral pathogens contribute to the progression of oral cancer
This study is looking at how certain bacteria in your mouth might affect the growth of oral cancer, and it’s for people who have or are at risk for oral squamous cell carcinoma, as they may help by sharing samples or information about their oral health.
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Exploring the role of anaerobic bacteria in health and disease
This study is looking at tiny germs that live without oxygen to see how they affect our health, especially in areas like oral cancer, gut health, and the effects of opioid withdrawal in teens, so we can learn more about how they might help us stay healthy.
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