Sponsor or institution
Clinical trials and research at Arkansas Children's Hospital Res Inst
As of November 12, 2026, Find a Trial lists 67 NIH-funded research projects at this institution, with $35.1 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 67NIH research projects
NIH-funded research (newest 40 of 67)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Shorter antifungal treatment for kids with candidemia
A multi-center pediatric trial tests whether a shorter, 7 extra days of antifungal therapy after an initial 7 days is just as good as the standard 14-day approach for kids with candidemia who are improving on echinocandin therapy.
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Short Course vs Standard Course Antifungal Therapy for Pediatric Candidemia
This study tests whether a shorter 7-day total antifungal treatment after an initial 7 days of echinocandin therapy is as effective as the usual 14-day course for children with candidemia.
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Shorter antifungal treatment for kids with candidemia
A multi-center study tests whether kids with candidemia can finish treatment earlier after an initial week of antifungal therapy than the standard two weeks total.
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Shorter antifungal treatment for kids with candidemia
This study tests whether children with candidemia can finish treatment after 7 days of an echinocandin if they are improving, instead of completing a full 14 days.
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Shorter antifungal course for kids with candidemia
A multi-center study tests whether 7 extra days of antifungal therapy after an initial week of treatment can be shortened safely for children with candidemia.
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Shortened antifungal treatment for kids with candidemia
A pediatric multicenter trial will test whether stopping antifungal therapy after 7 more days, following an initial 7 days of treatment, isas safe as continuing for 14 days.
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PRELUDE: Understanding how early life experiences shape child brain development
This nationwide study follows mothers and babies from before birth to age 10 to learn how experiences in pregnancy and early childhood affect brain development and behavior.
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Short Course vs Standard Course Antifungal Therapy for Pediatric Candidemia
A pediatric-focused clinical trial tests whether a shorter duration of antifungal therapy after initial improvement is as good as the standard 14-day approach for kids with candidemia.
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Short versus standard antifungal treatment for children with Candida bloodstream infections
This trial compares a shorter antifungal course to the usual 14-day course for children with Candida in the blood who improve after the first week of echinocandin treatment.
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Short versus standard antifungal treatment for children with bloodstream Candida infection
This trial compares whether children with bloodstream Candida infections can be safely treated with a shorter 7-day antifungal course instead of the usual 14 days.
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Short versus standard antifungal treatment for children with Candida bloodstream infections
This compares giving one extra week versus the usual two extra weeks of antifungal medicine for children whose Candida bloodstream infection clears after initial treatment.
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Short versus standard antifungal treatment for children with candidemia
This trial tests whether children with bloodstream Candida infections who improve after one week of echinocandin therapy can safely stop after a total of 7 days instead of the usual 14 days.
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Shorter antifungal treatment for children with Candida bloodstream infections
This compares a shorter 7-day versus the usual 14-day antifungal treatment for children whose Candida blood infections have cleared after initial therapy.
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Shorter antifungal treatment for children with Candida bloodstream infection
This compares a shorter (7-day) versus the usual 14-day antifungal course for children whose blood cultures for Candida have cleared after initial treatment.
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Arkansas pediatric clinical trials hub for child health in Arkansas
A pediatric-focused clinical trials site in Arkansas helps rural kids access cutting-edge research to improve their health.
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Digital and Hormonal Biomarkers to Personalize Smoking Cessation for Women of Reproductive Age
A study aims to use hormonal and digital biomarkers to tailor smoking cessation therapies for women in their reproductive years.
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Understanding how kidney toxins and sex affect kidney disease in Alport syndrome
This project looks at why some kids with Alport syndrome have faster kidney decline and whether sex (male or female) changes the impact of waste products that build up when the kidneys don’t work well.
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Understanding how nerve signals become painful after injury by studying skin and nerve cells
This grant looks at how changes in gene regulation in pain-related nerve cells after injury might explain persistent pain and point to new ways to treat it.
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MED12L-associated chromatin changes in a pediatric leukemia linked to poor outcomes
This grant explores how specific gene-related changes drive a dangerous pediatric leukemia and aims to uncover new angles for better treatments.
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Proteogenomics Core for pediatric translational research
A new Proteogenomics Core will give pediatric researchers access to expert bioinformatics, proteomics, genomics, and epigenomics analyses to speed up translational studies.
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Administrative Core supporting pediatric translational research at Arkansas Children’s Hospital
A funding program provides leadership and infrastructure support to a pediatric translational research center to help researchers in Arkansas develop and sustain pediatric science.
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Translational Pediatric Research Center for Cancer & Proteogenomics
A pediatric cancer-focused center in Arkansas is building advanced bioinformatics and proteogenomic methods to identify epigenomic targets and potential therapies for kids.
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Markers of neurocognitive changes during chemotherapy in children with ALL
A research project looks at how chemotherapy affects thinking skills in kids with acute lymphoblastic leukemia, to help families understand and guide care.
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Mitochondria and metabolism after burn injury
Researchers are exploring how tiny energy centers in cells called mitochondria change metabolism after severe burns to help people recover faster.
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Making preschool and daycare mealtimes healthier for young children
A program to help preschool and daycare staff stop common feeding habits that can harm 3- to 5-year-olds' eating and weight.
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Understanding CFTR Modulators in Pregnancy for Moms and Babies
We’re studying how CFTR-modifying medicines behave in pregnant people with cystic fibrosis and what that means for moms and their babies.
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Ensuring Access to Optimal Therapy in CF: ENACT study
A CF study to understand and improve how people with cystic fibrosis respond to a triple therapy by looking at drug levels and genetics to guide dosing.
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How calcineurin controls Aspergillus fumigatus’ antifungal defense
This grant studies how a fungal cell’s internal signaling pathway controls its defense against antifungal drugs so we can fight invasive Aspergillus infections.
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Host and microbe signals to predict SARS-CoV-2 and severe disease in children with viral coinfections
A study to help doctors predict which children with multiple respiratory viruses, including SARS-CoV-2, are most at risk for severe illness using a gene-based classifier.
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Partial heart transplant to give growing heart valves to children
This work tries transplanting only the donor heart part that contains a valve so children can get a valve that grows with them.
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New treatments for lymphatic malformations in children
Targeted, personalized drug approaches and lab testing aim to find safer, more effective treatments for children with cystic lymphatic malformations.
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Understanding how our bodies and germs affect COVID-19 risk and symptoms
This research looks at how the tiny germs living in our airways and our own genes might make some healthy people more or less likely to get sick with COVID-19.
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Arkansas center focused on improving prevention and treatment for food allergies
This center will work to create better prevention and treatment options for children and adults with food allergies, including peanut allergy and tick‑related alpha‑gal syndrome.
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Prenatal PFAS exposure, placental changes, and whether maternal exercise helps infants' growth and development
This project looks at whether PFAS chemical exposure before and after birth changes babies' growth, body fat, and early thinking skills, and whether a mother's physical activity during pregnancy can reduce those effects.
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Mobile Centering Pregnancy program for Marshallese mothers in Arkansas
Offers mobile group prenatal care to pregnant Marshallese women in Arkansas to improve mothers' and babies' health.
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Childhood Obesity Prevention Center
This center works to develop and test ways to prevent and reduce obesity in children and teens, especially in Arkansas.
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Protecting children with transplants from respiratory viruses
This project follows children having organ or stem-cell transplants to track viruses and immune responses so doctors can better predict and prevent serious lung infections.
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PlexinA2 and long-lasting nerve pain
Researchers are looking at a protein called PlexinA2 to understand why nerve injuries lead to persistent neuropathic pain for some people.
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How MED12L-linked DNA switches affect infant megakaryoblastic leukemia
This work tests whether MED12L-related changes in DNA regulation drive aggressive megakaryoblastic leukemia in infants and young children.
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How the HELB protein helps protect DNA when cells copy themselves
This project looks at whether the HELB protein helps cells protect and copy their DNA, which could matter for people at risk of cancer or age-related tissue damage.
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