Translational Pediatric Research Center for Cancer & Proteogenomics
Official title: Center for Translational Pediatric Research
Funded at Arkansas Children's Hospital Res Inst · NIH-11386596 · Data updated 2026-11-12
A pediatric cancer-focused center in Arkansas is building advanced bioinformatics and proteogenomic methods to identify epigenomic targets and potential therapies for kids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arkansas Children's Hospital Res Inst NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project start | July 11, 2017 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $2,056,179 |
| NIH project number | 5P20GM121293-10 |
| Project ID | NIH-11386596 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pediatric cancer patients or children at risk who may benefit from future targeted therapies or biomarker-driven approaches.
✕Less likely to help
Young patients with cancers not yet linked to the center's proteogenomic targets may not directly benefit.
What this research studies
This program uses systems biology and proteogenomics to understand how epigenetic changes drive pediatric cancers and to find new therapeutic targets. It supports core resources in proteomics and genomics/bioinformatics, plus a mentored development plan for junior investigators. The goal is to translate laboratory discoveries into clinically meaningful advances for children, with an emphasis on sustainability and collaboration across disciplines. The center has evolved from Phase I to Phase II, expanding members, cores, and external funding to strengthen translational output.
Why it matters
Potential benefit: If successful, the center could help identify new treatments and biomarkers for pediatric cancers and accelerate their movement toward the clinic.
How similar studies have gone: Previous COBRE centers have trained investigators and established sustainable cores, with some transitioning to larger extramural funding and translational outputs.
Where this research is happening
-
Arkansas Children's Hospital Res Inst
Little Rock, United States Active
Researchers
- Principal investigator: Tackett, Alan — Arkansas Children's Hospital Res Inst
- Study coordinator: Tackett, Alan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.