NIH-funded research U01 cooperative agreement

Arkansas center focused on improving prevention and treatment for food allergies

Official title: Arkansas Center for Food Allergy Research (ArCOFAR)

Funded at Arkansas Children's Hospital Res Inst · NIH-11283973 · Data updated 2026-11-12

This center will work to create better prevention and treatment options for children and adults with food allergies, including peanut allergy and tick‑related alpha‑gal syndrome.

More Allergy research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionArkansas Children's Hospital Res Inst
NIH-funded
Lab location1 site (Little Rock, United States)
Project startMarch 14, 2024
Project endFebruary 28, 2031
Funding year2026
Award (this year)$640,028
NIH project number5U01AI181962-03
Project IDNIH-11283973 on NIH RePORTER

Who could benefit from this research

Could help

Children and adults with food allergies—such as peanut allergy, eosinophilic gastrointestinal disorders, or suspected alpha‑gal syndrome—or those at high risk who can travel to Arkansas or nearby CoFAR sites are ideal candidates.

Less likely to help

People without food allergies or with health issues unrelated to allergic disease are unlikely to receive direct benefits from this center's work.

What this research studies

At Arkansas Children's Hospital, this center will run clinical studies and trials aimed at improving how food allergies are prevented and treated. If you join, researchers will enroll children and adults—especially people from rural and underserved communities—and collect health information and biological samples to learn what helps. The team brings over 30 years of experience with peanut immunotherapy and eosinophilic gastrointestinal disorders and will include patients with alpha‑gal syndrome common in the region. Their work is intended to translate study findings into treatments and prevention options that could be used more widely.

Why it matters

Potential benefit: If successful, this work could produce new prevention strategies and more effective treatments for food allergies and improve access for rural and underserved patients.

How similar studies have gone: Related efforts like peanut immunotherapy have shown promising results, though prevention strategies and work on conditions like alpha‑gal and EGID remain an active area of research.

Where this research is happening

  • Arkansas Children's Hospital Res Inst
    Little Rock, United States
    Active

Researchers

  • Principal investigator: Jones, Stacie M — Arkansas Children's Hospital Res Inst
  • Study coordinator: Jones, Stacie M

Related research

Other NIH-funded projects on the same topics.

  • New Horizons in preventing and treating food allergy

    A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

  • New Horizons in Food Allergy Prevention and Treatment

    A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11580809

  • Food allergy outcomes by race/ethnicity from infancy through adolescence

    This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.

    NIH research Northwestern University · Chicago, United States · NIH-11579222

  • Gut-brain links in food allergy responses

    A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.

    NIH research Yale University · New Haven, United States · NIH-11551492

  • Targeting gut microbes to restore food-tolerance in adults

    Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11551491

  • Environment and early-life exposures shaping food allergy in children

    This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11450430

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.