Venous clots after trauma: finding who’s at risk and how to prevent them
Official title: Venous Thrombosis After Traumatic Injury
Funded at Mayo Clinic Rochester · NIH-11378463 · Data updated 2026-11-12
This grant aims to understand why people who have experienced serious injuries develop dangerous blood clots after leaving the hospital, and how to predict and prevent those events.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $644,193 |
| NIH project number | 5R01HL162729-04 |
| Project ID | NIH-11378463 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with traumatic injuries receiving hospital care who consent to participate and provide blood samples and related data.
✕Less likely to help
Patients who do not experience bleeding or clotting issues after trauma may not directly benefit from the findings.
What this research studies
If you’ve had a traumatic injury, researchers want to study how your blood clots after the injury and during recovery. They plan to collect and analyze blood tests, medical data, and patient characteristics (like sex, BMI, and smoking) in real time to identify factors that raise the risk of clotting or bleeding. The goal is to create better ways to predict who is at risk and to guide more effective monitoring and treatment. This work would involve collaboration across clinics and labs to gather comprehensive information from diverse trauma patients.
Why it matters
Potential benefit: If successful, the research could lead to personalized monitoring and better prevention strategies for VTE after trauma.
How similar studies have gone: Previous research has shown that integrating lab data with patient characteristics can improve risk prediction for clotting in trauma, but real-time, comprehensive approaches are still emerging.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Park, Myung Soo — Mayo Clinic Rochester
- Study coordinator: Park, Myung Soo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.