NIH-funded research R21 grant

Using a simple breathing test to check lung function after kids’ acute respiratory failure

Official title: Use of Oscillometry for the Evaluation of Pulmonary Function Following Pediatric Acute Respiratory Failure.

Funded at Seattle Children's Hospital · NIH-11530755 · Data updated 2026-11-12

A study will test a child-friendly breathing method (oscillometry) to check how well lungs work after severe respiratory illness in kids.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSeattle Children's Hospital
NIH-funded
Lab location1 site (Seattle, United States)
Project startMay 1, 2025
Project endApril 30, 2027
Funding year2026
Award (this year)$31,004
NIH project number3R21HD118297-02S1
Project IDNIH-11530755 on NIH RePORTER

Who could benefit from this research

Could help

Children who survived acute respiratory failure from illnesses such as pneumonia or bronchiolitis, including those under 6 years old or with cognitive impairment.

Less likely to help

Healthy children without a history of acute respiratory failure or lung disease would not be the target population.

What this research studies

This project looks at how well oscillometry, a noninvasive breathing test, can measure lung function in children who survived acute respiratory failure from illnesses like pneumonia or bronchiolitis. It focuses on young children, including those under 6 or with cognitive challenges, for whom standard spirometry is hard to perform. The study will compare oscillometry results to traditional tests and see if this approach can be used in hospital and clinic settings to monitor recovery. By understanding long-term lung health in these patients, clinicians may tailor follow-up care more effectively.

Why it matters

Potential benefit: If successful, this method could make it easier to monitor lung recovery in many children, including those who can’t perform traditional tests.

How similar studies have gone: Previous small studies show oscillometry can detect lung changes; this study aims to expand and validate its use in pediatric survivors.

Where this research is happening

  • Seattle Children's Hospital
    Seattle, United States
    Active

Researchers

  • Principal investigator: Killien, Elizabeth Y — Seattle Children's Hospital
  • Study coordinator: Killien, Elizabeth Y

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.