NIH-funded research R21 grant

Using a simple breathing test to check how kids recover lung function after severe lung illness

Official title: Use of Oscillometry for the Evaluation of Pulmonary Function Following Pediatric Acute Respiratory Failure.

Funded at Seattle Children's Hospital · NIH-11324603 · Data updated 2026-11-12

A study will test a quick, noninvasive breathing test called oscillometry to see how well children who survived dangerous lung problems recover over time.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSeattle Children's Hospital
NIH-funded
Lab location1 site (Seattle, United States)
Project startMay 1, 2025
Project endApril 30, 2027
Funding year2026
Award (this year)$197,700
NIH project number5R21HD118297-02
Project IDNIH-11324603 on NIH RePORTER

Who could benefit from this research

Could help

Children who survived acute respiratory failure or pediatric ARDS and are being followed after ICU discharge, including those under 6 years old or with cognitive impairments.

Less likely to help

Children without a history of acute respiratory failure or unrelated lung conditions are not the target of this study.

What this research studies

This project focuses on children who survived acute respiratory failure from illnesses like pneumonia or bronchiolitis. It will evaluate whether oscillometry, a gentle breathing test, can measure lung function in kids who are younger than 6 or have cognitive challenges. By following these children after ICU discharge, researchers aim to understand long-term lung health where traditional spirometry isn’t feasible. The study will compare oscillometry results with existing lung function data to see if this method could be used more broadly in pediatric care.

Why it matters

Potential benefit: If successful, oscillometry could become a routine, child-friendly way to monitor lung recovery after critical illness.

How similar studies have gone: Prior studies show oscillometry is feasible in children and could reflect lung function, but this exact application after pediatric critical illness is being explored.

Where this research is happening

  • Seattle Children's Hospital
    Seattle, United States
    Active

Researchers

  • Principal investigator: Killien, Elizabeth Y — Seattle Children's Hospital
  • Study coordinator: Killien, Elizabeth Y

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.