Using a simple breathing test to check how kids recover lung function after severe lung illness
Official title: Use of Oscillometry for the Evaluation of Pulmonary Function Following Pediatric Acute Respiratory Failure.
Funded at Seattle Children's Hospital · NIH-11324603 · Data updated 2026-11-12
A study will test a quick, noninvasive breathing test called oscillometry to see how well children who survived dangerous lung problems recover over time.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | May 1, 2025 |
| Project end | April 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $197,700 |
| NIH project number | 5R21HD118297-02 |
| Project ID | NIH-11324603 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children who survived acute respiratory failure or pediatric ARDS and are being followed after ICU discharge, including those under 6 years old or with cognitive impairments.
✕Less likely to help
Children without a history of acute respiratory failure or unrelated lung conditions are not the target of this study.
What this research studies
This project focuses on children who survived acute respiratory failure from illnesses like pneumonia or bronchiolitis. It will evaluate whether oscillometry, a gentle breathing test, can measure lung function in kids who are younger than 6 or have cognitive challenges. By following these children after ICU discharge, researchers aim to understand long-term lung health where traditional spirometry isn’t feasible. The study will compare oscillometry results with existing lung function data to see if this method could be used more broadly in pediatric care.
Why it matters
Potential benefit: If successful, oscillometry could become a routine, child-friendly way to monitor lung recovery after critical illness.
How similar studies have gone: Prior studies show oscillometry is feasible in children and could reflect lung function, but this exact application after pediatric critical illness is being explored.
Where this research is happening
-
Seattle Children's Hospital
Seattle, United States Active
Researchers
- Principal investigator: Killien, Elizabeth Y — Seattle Children's Hospital
- Study coordinator: Killien, Elizabeth Y
Related research
Other NIH-funded projects on the same topics.
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Using a simple breathing test to check lung function after kids’ acute respiratory failure
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Helping survivors of acute respiratory failure manage anxiety
This study is looking to help adults who have recovered from serious breathing problems feel less anxious by trying out a new self-help program, and it will start by talking to patients in the hospital to make sure the program meets their needs before testing it against regular care.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.