Understanding how brain connectivity changes after DBS for essential tremor

Who could benefit from this research

What this research studies

This project follows adults with essential tremor who have DBS implants to the dentato-rubrothalamic tract area. It uses advanced brain imaging to map structural and functional brain connections before and after DBS over several years to understand how stimulation affects the cerebellar-thalamic-cortical network. The researchers aim to link changes in brain connectivity with tremor outcomes and potential gait side effects to improve targeting and programming of DBS. The study builds on prior imaging advances that helped guide DBS placement and seeks to refine our understanding of ET pathology and treatment effects.

Why it matters

Where this research is happening

• Feinstein Institute for Medical Research
  Manhasset, United States Active

Researchers

• Principal investigator: Fenoy, Albert J — Feinstein Institute for Medical Research
• Study coordinator: Fenoy, Albert J

Related research

Other NIH-funded projects on the same topics.

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.