New deep brain stimulation technique for treating essential tremor

Who could benefit from this research

What this research studies

This research investigates a novel deep brain stimulation technique called Coordinated Reset (CR) stimulation for patients with essential tremor, a condition that causes involuntary shaking. The study aims to reduce side effects associated with traditional stimulation methods by using lower current amplitudes and alternating stimulation across multiple contacts in the brain. By targeting the cerebello-thalamo-cortical network, this approach seeks to minimize unwanted effects like dysarthria and ataxia while providing effective tremor relief. Patients will be monitored for both immediate and long-term benefits from this innovative treatment.

Why it matters

Where this research is happening

• University of Minnesota
  Minneapolis, United States Active

Researchers

• Principal investigator: Wang, Jing — University of Minnesota
• Study coordinator: Wang, Jing

Related research

Other NIH-funded projects on the same topics.

• Thalamic Coordinated Reset Deep Brain Stimulation for Essential Tremor

  A new brain stimulation approach is being tested to help people with essential tremor by using coordinated, lower-intensity stimulation to the thalamus.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11263676

• New deep brain stimulation technique for treating essential tremor

  This study is testing a new way to use deep brain stimulation to help people with essential tremor by using a gentler method that aims to reduce side effects, so you can feel better without as many complications.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11223028

• Understanding how brain connectivity changes after DBS for essential tremor

  A study of how deep brain stimulation in essential tremor patients changes brain connections over time and how this relates to long-term tremor control and side effects.

  NIH research Feinstein Institute for Medical Research · Manhasset, United States · NIH-11146409

• Vocal Tremor in Essential Tremor: Understanding Physiologic Cues in Older Adults

  This grant studies why and how vocal tremor happens in people with essential tremor, aiming to better understand and describe voice changes in older adults.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11530720

• New therapies for essential tremor from cannabidiol mechanisms

  A patient-facing overview of how cannabis-based medicines might help tremor by targeting specific brain receptors, aiming to find better and better tolerated treatments for essential tremor.

  NIH research VA Greater Los Angeles Healthcare System · Los Angeles, United States · NIH-11517167

• Test to flag essential tremor patients at risk of Parkinson’s progression by detecting phosphorylated alpha-synuclein

  A new test being developed for people with essential tremor to see who might later develop Parkinson’s disease.

  NIH research Cnd Life Sciences, INC. · Scottsdale, UNITED STATES · NIH-11401181

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.