UAB Childhood Cystic Kidney Disease Center Resource Hub
Official title: UAB Childhood Cystic Kidney Disease Center (UAB-CCKDC) - Resource Development Core
Funded at University of Alabama at Birmingham · NIH-11416776 · Data updated 2026-11-12
A specialized center will develop and validate new tools and resources to help researchers study childhood polycystic kidney diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | July 20, 2020 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $26,019 |
| NIH project number | 5U54DK126087-07 |
| Project ID | NIH-11416776 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include researchers and clinicians studying ADPKD or ARPKD who need new animal models, stem cell-derived kidney organoids, or other PKD resources.
✕Less likely to help
Patients not directly involved in PKD research may not receive immediate direct benefits from this core.
What this research studies
This project creates a dynamic incubator within the UAB CCKDC to develop and validate new PKD resources, including mouse/rat models and kidney organoids from stem cells. It will prioritize resources that aren’t already available in other PKD cores, guided by a steering committee. The goal is to accelerate shared, high-quality tools that can help advance therapies for ADPKD and ARPKD. By enabling robust resource generation, researchers can faster translate discoveries into potential treatments for patients. The RDC will collaborate with other PKD centers to ensure broad applicability and validation.
Why it matters
Potential benefit: Patients could benefit from faster development of validated model systems and organoids that support drug testing and understanding disease biology.
How similar studies have gone: Past PKD resource cores have enabled meaningful advances by providing validated tools; this center aims to expand and diversify those resources.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Parant, John M — University of Alabama at Birmingham
- Study coordinator: Parant, John M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.