UAB Childhood Cystic Kidney Disease Center: Advancing PKD Care from Childhood to Translation
Official title: UAB Childhood Cystic Kidney Disease Center (UAB-CCKDC)
Funded at University of Alabama at Birmingham · NIH-11416743 · Data updated 2026-11-12
A dedicated center at the University of Alabama at Birmingham is building resources to understand and treat polycystic kidney disease starting in childhood, with data, patient care insights, and new model systems to speed therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | July 20, 2020 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $775,416 |
| NIH project number | 5U54DK126087-07 |
| Project ID | NIH-11416743 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with childhood PKD or a related renal cystic condition who may contribute samples or participate in future clinical studies.
✕Less likely to help
Patients without access to specialized PKD care centers or who do not have a childhood PKD focus may see limited direct benefits.
What this research studies
This grant supports a center focused on childhood polycystic kidney disease (PKD) within a national research network. It will collect patient data and biomaterials, harmonize them in a centralized database, and develop tools to study patient experiences to guide patient-centered research. The team will create new animal and human cell models, including kid-friendly organoids, to study cyst formation and test potential treatments. A data analytics hub will enable large-scale analysis of omics data to identify targets and pathways. The work aims to translate discoveries into better care and outcomes for children and, ultimately, for PKD patients as they age.
Why it matters
Potential benefit: If successful, patients with PKD could benefit from faster translation of scientific discoveries into improved diagnostics and treatments.
How similar studies have gone: Prior PKD centers have advanced collaborative data resources and animal/human models that accelerated translational work, suggesting potential for meaningful progress here.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Yoder, Bradley K. — University of Alabama at Birmingham
- Study coordinator: Yoder, Bradley K.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.