Thrombosis and Bleeding Risk in Medical Inpatients
Official title: Thrombosis and Bleeding Risk Assessment in Medical Inpatients
Funded at University of Vermont & St Agric College · NIH-11366383 · Data updated 2026-11-12
A patient-facing program to better predict who is at risk for blood clots or bleeding during and after hospital stays, and to tailor prevention accordingly.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Vermont & St Agric College NIH-funded |
| Lab location | 1 site (Burlington, United States) |
| Project start | September 15, 2019 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $845,134 |
| NIH project number | 2R01HL141290-05A1 |
| Project ID | NIH-11366383 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults hospitalized for medical conditions who are at risk of venous thromboembolism or bleeding and are candidates for prophylaxis.
✕Less likely to help
Patients not at risk for VTE or bleeding or those not considered for prophylaxis may see limited benefit.
What this research studies
This project aims to improve how clinicians estimate bleeding and clotting risk for adults admitted for medical problems. It will combine patient experiences with clinical risk scores and results from randomized trials to guide safer, personalized prevention strategies. The work spans hospital care and after discharge across four health systems, with thousands of admissions involved. It seeks to put patient values at the center of decision making while reducing unnecessary bleeding or missed clots.
Why it matters
Potential benefit: If successful, this approach could help doctors choose safer, more effective ways to prevent clots and bleeding for hospitalized patients.
How similar studies have gone: Previous work identified limitations in existing RAMs and demonstrated distinct bleeding phenotypes, informing the current renewal.
Where this research is happening
-
University of Vermont & St Agric College
Burlington, United States Active
Researchers
- Principal investigator: Zakai, Neil Adrian — University of Vermont & St Agric College
- Study coordinator: Zakai, Neil Adrian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.