Sponsor or institution
Clinical trials and research at University of Vermont & St Agric College
As of November 12, 2026, Find a Trial lists 221 NIH-funded research projects at this institution, with $123.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 221NIH research projects
NIH-funded research (newest 40 of 221)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Diet-friendly gut bacteria: testing high-fiber ideas to boost infection resistance
A researcher team will test how high-fiber foods and specific dietary fibers can help the gut microbiome protect against gut infections using a fast, lab-based model.
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Co-treated care for substance use and heart infection at UVMMC
A hospital-based project aims to improve how doctors and teams treat people with both substance use disorder and infective endocarditis during their hospital stay.
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Adipose tissue and its role in lung cancer cachexia
A new NIH grant explores how fat tissue around the body may feed lung cancer growth and drive weight loss, with the aim of finding ways to help patients who struggle with cancer cachexia.
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Accessing strained rings and heterocycles to make new bacterial metabolites and building blocks
Scientists are developing new ways to make unusual ring-shaped molecules to create rare bacterial metabolites and ready-to-use chemical building blocks that could influence health.
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Gene expression marks high risk for very late breast cancer return
A patient-focused study aims to find gene patterns that identify women with early breast cancer who are most likely to have cancer come back more than a decade later.
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Healthy Brain and Child Development study across 27 sites
A nationwide study follows mothers and infants from pregnancy through early childhood to map how genes and environments shape brain development and behavior.
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Orally delivered compounds to treat cryptosporidiosis in vulnerable patients
A new oral drug candidate is being developed to treat cryptosporidiosis, especially in children and people with weakened immune systems.
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Continued Clinical Development of a Novel Pleural and Tracheal Sealant
A new adhesive patch made from seaweed-derived materials is being developed to seal lung air leaks and prevent complications after chest injuries or mechanical ventilation.
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Understanding how a tiny muscle motor changes shape and pace one molecule at a time
Scientists are studying a muscle protein called myosin to see how it switches between calm and active states, which could affect how muscles work and breathe.
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Salmonella inside gut cells: uncovering bacterial genes that help it live in the intestines and gallbladder
A small early-stage NIH grant aims to find specific Salmonella genes that let the bacteria live inside gut and gallbladder cells, which could inform future ways to prevent or treat infections.
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Dynamic patterns of oral nicotine pouch use and tobacco transitions in adults
A long-term study is following adults to understand how people start, switch, or stop using oral nicotine pouches, cigarettes, and other tobacco products.
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Using gene expression to identify patients at high risk for late breast cancer recurrence
Researchers are studying breast cancer patients to find gene patterns that predict who might have cancer come back many years later, so doctors can tailor care for those at highest risk.
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DNA damage repair in cancer: how damaged DNA is identified and fixed
A cancer-focused grant exploring how cells recognize and repair damaged DNA to understand why tumors form and how treatments work.
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How stress and injury affect bladder control and pain
This research explores how stress and injury change brain circuits and bladder signals to worsen bladder pain and urinary symptoms in people with bladder pain syndrome.
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Structure and function of the Plasmodium glideosome motor
Researchers are studying how the malaria parasite moves inside humans to identify new ways to stop infection, with potential benefits for children under 5.
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Gene tests to find women at high risk of breast cancer returning many years later
This project looks for patterns in tumor gene activity to spot women with ER-positive breast cancer who are more likely to have the cancer come back more than 10 years after initial treatment.
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HIV-1 small T cell syncytia and how they spread virus
A research study at a university will look at tiny, multi-nucleus T cells that HIV-1 forms early after infection to see how they move and pass the virus to other cells.
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A newer, smarter vaccine delivery system for COVID-19 vaccines
This grant explores how lipid nanoparticles used in vaccines influence the immune response and how to design better vaccines for people.
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Mathematical and Computational Modeling Core for Global Infectious Disease Research
A core group at the University of Vermont helps researchers use math and computer models to understand and fight global infectious diseases like COVID-19.
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Human and Population Research Core (HPR Core) for infectious disease research
A core facility helps researchers study infectious diseases by providing biostatistics, data management, biorepository services, and expert guidance to develop new clinical projects.
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Administrative Core for a Center of Biomedical Research Excellence in Global Infectious Diseases
This grant funds an Administrative Core to support junior investigators and strengthen infectious disease research at a collaborative regional center.
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Translational Global Infectious Diseases Research Center (TGIR COBRE)
A nationwide effort at the University of Vermont to strengthen infectious disease research that helps scientists translate findings into real-world prevention and care, especially in low-resource settings.
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Understanding how small brain vessels fail and contribute to dementia
A research project is exploring how loss of smooth muscle cells in brain vessels leads to cognitive problems and dementia.
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Proteomics Core for Advanced Protein Studies
A proteomics core facility at the University of Vermont supports advanced protein research for regional researchers and students using mass spectrometry and related techniques.
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Administrative Core for a Center for Biomedical Research Excellence
A central team helps manage a multi-institution research program, keeping finances, communications, and oversight running smoothly so researchers and students can focus on biomedical work.
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Vermont Biomedical Research Network supports student-focused science in Vermont
A statewide program helps colleges train undergraduates, upgrade research facilities, and grow biomedical research across Vermont for the benefit of students and the community.
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How arenaviruses’ defective particles help protect hosts and how our cells control them
This project studies how defective virus particles produced by arenaviruses influence infections and the body’s own cellular processes, with a focus on factors that regulate their formation and function in the host.
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Making clinical trials easier for rural kids in Vermont
A program to help children in rural Vermont participate in pediatric clinical trials through local clinics, schools, and community groups.
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Breast cancer risk tools to guide management of high-risk benign breast lesions
Aims to improve how doctors decide which women with high-risk benign breast lesions can safely avoid surgery while keeping cancer risk low.
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MyBP-C and heart muscle: how protein balance affects heart function
This project looks at how low levels of a heart protein called MyBP-C affect heart muscle performance and structure, especially in people with hypertrophic cardiomyopathy.
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Mid-Life Health in Rural America: Risk and Resilience
A study in rural North Carolina and surrounding areas aims to understand why health differences emerge in mid-life among African American and White adults, by following people over time and collecting health, cognitive, and life context data.
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How a mother’s infection during pregnancy shapes baby’s immune cells
A mother’s infection or inflammation during pregnancy may change how a baby’s immune system develops, especially a special type of immune cell called γδ T cells.
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Understanding how cellular cargo gets moving along microtubules
A researcher at a university is studying how cells transport their parts along internal highways so proper cell function and nerve health are maintained.
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Sex hormones and stroke: a personalized risk map for men and women
Aims to link sex hormones to stroke risk and build sex-specific prediction tools to prevent stroke for people in diverse populations.
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Tele-exercise to help prostate cancer: a home-based group workout for World Trade Center responders
A remote, live online exercise program helps World Trade Center responders with prostate cancer improve physical function from home.
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Personalized supplemental breast imaging for dense breasts
A research project tests whether adding ultrasound or MRI screening for women with dense breasts helps find cancers earlier and in a way that protects against unnecessary tests.
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A gut bacteria vitamin K link to MS progression
A small NIH-funded study will look at how a gut bacteria, Akkermansia muciniphila, and its vitamin K production relate to multiple sclerosis progression in people affected by MS.
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Optimizing aerobic fitness and how older adults respond to exercise
This grant tests exercise programs to help older adults with daily activities improve their heart health and physical function after hospital stays.
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Fecal microbiome therapy to help older adults recover after brain injury
A trial explores giving a healthy gut microbiome to help people, especially older adults, recover better after a traumatic brain injury.
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Mechanistic insights into how a DNA damage bypass enzyme influences genome stability
This NIH grant studies how the REV1 enzyme, involved in bypassing DNA damage, affects genome stability and cell fate with potential links to cancer and infectious diseases.
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