Temple University Gastroparesis Clinical Center: Advancing Understanding and Care
Official title: Temple University Gastroparesis Clinical Center
Funded at Temple Univ of the Commonwealth · NIH-11386478 · Data updated 2026-11-12
A patient-centered grant from NIH supports Temple University to enroll people with gastroparesis in ongoing studies to better understand causes and improve treatments.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | April 15, 2006 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $293,516 |
| NIH project number | 5U01DK073975-20 |
| Project ID | NIH-11386478 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with gastroparesis who are enrolled in the GpCRC studies or eligible for the GpR3 registry and related ancillary studies.
✕Less likely to help
Patients not eligible for the registry or ongoing trials may not directly benefit from this particular program.
What this research studies
Temple University leads as a clinical center in a national network focused on gastroparesis. The project continues patient enrollment and long-term follow-up, with registries and ancillary studies to explore immune and pyloric factors. Participants may contribute data, biopsy samples, and responses to treatments like Buspirone for early satiety, while researchers study SARS-CoV-2 effects on gastroparesis and underlying immune profiles. The goal is to translate findings into more effective care for people living with gastroparesis.
Why it matters
Potential benefit: If successful, patients could receive more effective, tailored treatments and clearer symptom relief.
How similar studies have gone: Previous multicenter gastroparesis studies have advanced understanding and treatment options, with ongoing registries and ancillary studies building on prior findings.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Parkman, Henry Paul — Temple Univ of the Commonwealth
- Study coordinator: Parkman, Henry Paul
Related research
Other NIH-funded projects on the same topics.
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New England Gastroparesis Consortium: Neurobiology of Gastroparesis
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
-
Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
-
Pediatric gastroparesis: building a nationwide patient registry
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
-
Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
-
Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.