New England Gastroparesis Consortium: Neurobiology of Gastroparesis
Official title: New England Gastropareis Consortium: Neurobiology of Gastroparesis
Funded at Massachusetts General Hospital · NIH-11583186 · Data updated 2026-11-12
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 25, 2016 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $61,800 |
| NIH project number | 3U01DK112193-10S1 |
| Project ID | NIH-11583186 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with gastroparesis or gastroparesis-like syndromes, and adults with gastroparesis, who can participate in a national registry.
✕Less likely to help
Patients not fitting the registry criteria or who do not participate in follow-up would not directly benefit.
What this research studies
This grant supports a pediatric and adult gastroparesis registry to collect standardized information from patients with delayed stomach emptying. Researchers will enroll children and adults, track symptoms and quality of life, and compare Gp with related conditions like functional dyspepsia. The study outlines steps to build on an existing pediatric registry and create a national prospective registry to uncover factors that influence disease severity. Data from this effort could help doctors tailor care and improve outcomes for patients with gastroparesis and related disorders.
Why it matters
Potential benefit: If successful, this work could lead to better diagnosis, understanding, and management of gastroparesis across ages, improving daily life and health outcomes.
How similar studies have gone: Prior pediatric registries exist and this project aims to expand nationwide with standardized data to strengthen insights.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Burton Murray, Helen — Massachusetts General Hospital
- Study coordinator: Burton Murray, Helen
Related research
Other NIH-funded projects on the same topics.
-
Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
-
Pediatric gastroparesis: building a nationwide patient registry
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
-
Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
-
Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
-
Prucalopride for gastroparesis in adults: a multi-site trial
A multicenter study tests a medicine called prucalopride to help adults with gastroparesis feel better and have fewer stomach symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.