Pediatric gastroparesis: building a nationwide patient registry
Official title: Advancing Clinical Science in Pediatric Gastroparesis
Funded at Baylor College of Medicine · NIH-11567122 · Data updated 2026-11-12
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 25, 2016 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $344,404 |
| NIH project number | 3U01DK112194-10S1 |
| Project ID | NIH-11567122 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with gastroparesis or gastroparesis-like symptoms who meet pediatric Rome IV criteria and are part of the pediatric registry framework.
✕Less likely to help
Some participants may not experience immediate changes in treatment; the study focuses on data collection rather than direct intervention.
What this research studies
The project aims to create a national registry for children and adolescents with gastroparesis and gastroparesis-like symptoms, using pediatric Rome IV criteria to classify related conditions such as functional dyspepsia. By collecting standardized data on symptoms, treatment responses, and quality of life, researchers hope to reveal patterns that explain why some kids are more severely affected. The work builds on the existing Pediatric Gastroparesis Registry within the NIDDK Gastroparesis Consortium to extend pediatric insights beyond adults. This information could guide future trials and improve care strategies for affected families.
Why it matters
Potential benefit: If successful, the registry could lead to more tailored treatments and better quality of life for children with gastroparesis and related conditions.
How similar studies have gone: Previous pediatric registries have demonstrated value in describing patient populations and informing future research, though pediatric-specific data remains limited.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Preidis, Geoffrey a — Baylor College of Medicine
- Study coordinator: Preidis, Geoffrey a
Related research
Other NIH-funded projects on the same topics.
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New England Gastroparesis Consortium: Neurobiology of Gastroparesis
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
-
Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
-
Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
-
Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
-
Prucalopride for gastroparesis in adults: a multi-site trial
A multicenter study tests a medicine called prucalopride to help adults with gastroparesis feel better and have fewer stomach symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.